Results 31 to 40 of about 54,041 (265)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Signal-Based Dynamic Identification of Composite Steel–Concrete Bridges Using Short-Duration Records

open access: yesInfrastructures
Structural Health Monitoring (SHM) of existing bridges increasingly relies on dynamic measurements to assess structural performance and detect potential damage.
Mario Ferrara   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Influence of an Innovative Corrugated High-Strength Steel Profile on Soil–Steel Composite Bridges

open access: yesBuildings
Composite soil–steel corrugated bridges, which are widely used in road, railway, and civil engineering, are recognized as durable, sustainable, and cost-effective structures. Due to their interactions with the surrounding soil, relatively thin corrugated
Nerijus Bareikis, Algirdas Juozapaitis
doaj   +1 more source

Bending Performance of Prestressed Concrete Composite Girder Bridge with Steel Truss Webs

open access: yes工程科学与技术, 2022
To study the flexural behavior of prestressed concrete (PC) composite girder bridge with truss webs, the model test of PC composite girder bridge with truss webs for the flexural behavior was conducted.
Kangming CHEN   +4 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Deep Learning-Based Damage Detection on Composite Bridge Using Vibration Signals Under Varying Temperature Conditions

open access: yesApplied Sciences
The dynamic characteristics of bridges are not only influenced by structural damage but also by ambient environmental variations. If environmental factors are not incorporated into the detection algorithm, they may lead to false positives or false ...
Arjun Poudel   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Parameter Optimization and Bending Performance Analysis of a Corrugated Steel Plate-UHPC Composite Bridge Deck with PZ Shear Connectors

open access: yesAdvances in Materials Science and Engineering, 2022
Composite bridge decks consisting of steel plates and concrete are used to minimize fatigue cracking and damage of asphalt pavement of orthotropic steel bridge decks subjected to wheel loads.
Anhua Wang   +3 more
doaj   +1 more source

Seismic Reduction Analysis of Super-Long Span Suspension Bridge with Lattice Composite Tower and Damping System: A Case of Study for Qiongzhou Strait Bridge

open access: yesApplied Sciences, 2023
In this paper, we proposed a lattice composite tower damping system to reduce the seismic response of super-long-span suspension bridges. Taking the QiongZhou strait bridge as a case study, we evaluated seismic performances through a finite element ...
Yan Zheng   +3 more
doaj   +1 more source

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