Results 121 to 130 of about 2,614,926 (378)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Influence of interfacial shear strength on the mechanical properties of SiC fiber reinforced reaction-bonded silicon nitride matrix composites [PDF]

The influence of fiber/matrix interface microstructure and interfacial shear strength on the mechanical properties of a fiber-reinforced ceramic composite was evaluated.
Bhatt, Ramakrishna T.
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Formation of Composite Coatings during Detonation Spraying of Cr3C2 [PDF]

, 2023
Igor S. Batraev, Vladimir Yu. Ulianitsky, А. А. Штерцер, Dina V. Dudina, Arina V. Ukhina   +4 more
openalex   +1 more source

Anticorrosion Properties of Epoxy Composite Coating Reinforced by Molybdate-Intercalated Functionalized Layered Double Hydroxide

Journal of Composites Science, 2019
Herein, an intercalation modification technique is proposed to improve the anticorrosion performance of polymeric coatings. Molybdate, an inhibitor, was intercalated to bestow inhibitive attributes, while functionalization of the layered double hydroxide
Suman Chhetri, P. Samanta, N. C. Murmu, Tapas Kuila   +3 more
semanticscholar   +1 more source

Second Harmonic Generation for a Dilute Suspension of Coated Particles

, 2003
We derive an expression for the effective second-harmonic coefficient of a dilute suspension of coated spherical particles. It is assumed that the coating material, but not the core or the host, has a nonlinear susceptibility for second-harmonic ...
A.E. Neeves, C. Brosseau, C. Xu, D. Stroud, D. Stroud, D. Stroud, D.J. Bergman, H.B. Liao, H.S. Zhou, J.B. Jackson, J.E. Sipe, J.W. Haus, J.W. Haus, M. Breit, M. Lomascolo, O. Levy, P. M. Hui, P.M. Hui, P.M. Hui, R.D. Averitt, R.W. Boyd, T. Klar, V.M. Shalaev, V.M. Shalaev, X.C. Zeng, Y.Q. Li   +25 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Study on extreme sulfuration behavior of brush-electroplated silver-graphene composite coatings as the electrical contact materials for the outdoor high-voltage isolating switch

Journal of Materials Research and Technology
The silver-graphene (Ag-G) composite coating was successfully prepared on the copper substrate via the method of cyanide-free brush plating. When the sulfuration temperature is increased from −70 °C to 45 °C, the sulfuration degree of the Ag-G composite ...
Zhen Chen, Zhiguo Ye, Yi Ding, Guang Ma, Xinyuan Peng, Duosheng Li   +5 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source