Results 111 to 120 of about 50,371 (314)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Stability Analysis of Thin-Walled Perforated Composite Columns Using Finite Element Method. [PDF]

Materials (Basel), 2022
Falkowicz K.
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Cracking and tension field action in composite beams [PDF]

Two aspects of the behaviour of uncased composite 'T' beams of steel and concrete are considered. Flexural cracking in the reinforced concrete slab was studied by subjecting seven 350-mm deep composite beams to hogging bending moment.
Allison, Robert William
core  

Experimental Study on the Seismic Performance of Brick Walls Strengthened by Small-Spaced Reinforced-Concrete–Masonry Composite Columns

Buildings
Through low-cycle reciprocating tests on 11 masonry wall specimens strengthened using reinforced-concrete–masonry composite columns, the effects of the position of the composite column, height-to-width ratio, column reinforcement ratio, and axial load ...
Fengmin Xia, Kaozhong Zhao, Jihui Zhao, Xiangjin Cui   +3 more
doaj   +1 more source

Numerical Modelling of Geopolymer Concrete In-Filled Fibre-Reinforced Polymer Composite Columns Subjected to Axial Compression Loading. [PDF]

Materials (Basel), 2022
Veerapandian V, Pandulu G, Jayaseelan R, Sathish Kumar V, Murali G, Vatin NI.   +5 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysing the Confinement Effect in Hollow Core Steel-Concrete Composite Columns under Axial Compression. [PDF]

Materials (Basel), 2021
Šapalas A, Mudrov A.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Statistical calibration of safety factors for flexural stiffness of composite columns

, 2016
Composite column design is strongly influenced by the computation of the critical buckling load, which is very sensitive to the effective flexural stiffness (EI) of the column.
Hicks, Stephen J., Uy, Brian, Kang, Won-Hee, Aslani, Farhad, Lloyd, Ryan, Kang, Won-Hee (R16823), Hicks, Stephen   +6 more
core   +1 more source