Results 31 to 40 of about 919 (217)
Experimental Behaviour of Steel Tubular Columns for Varying in Filled Concrete
Archives of Civil Engineering, 2017 This paper investigates the behaviour of axially-loaded tubular columns filled with M20 grade concrete and partially replaced concrete. The parameters varying in the study are slenderness ratio (13.27, 16.58 & 19.9), and normal M20 grade concrete ...
Sangeetha P., Senthil R.
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Applied SciencesConcrete-encased steel composite columns are preferred for their exceptional ductility and strength, particularly in high-rise buildings. This research aims to enhance both the strength and ductility of these composite columns by increasing the height of
Elif Gökçe İnce, Fatih Mehmet Özkal
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
BuildingsTo investigate the axial compression behavior of composite columns with high-strength concrete-filled steel tube flanges and honeycombed steel web (STHHC) under load during freeze–thaw cycles, 48 full-scale composite column specimens were designed with ...
Jing Ji +9 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Experimental and numerical verification of the standard procedure for determining the load capacity of GFRP composite lighting columns [PDF]
Archives of Civil EngineeringThe main objective of the research was to validate the method for determining the load capacity of GFRP composite lighting columns under horizontal loads according to the EN 40-3-3:2013 standard.
Mirosław Broniewicz +2 more
doaj +1 more source