Results 111 to 120 of about 5,444,300 (333)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Research of NC Gear-hobbing Machining and Error Compensation

Jixie chuandong, 2015
According to the principles of various gear profile generation and gear generating error,the motion control structure of NC hobbing system for gear machining is optimized.
Jia Dongsheng, Zhao Jiali
doaj  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

COMPOSITE MODEL ERROR SOURCES IN DISCRETE CHANNELS OF DATA CONVERSION

Системный анализ и прикладная информатика, 2016
Designed component model of the source of errors in real discrete channels of data conversion, based on the joint use of the channel within dependent generalized errors and channel with correlated errors pack image on the background of independent errors.
Yu. D. Ivanov, B. V. Lozka, Е. O. Kozljuk   +2 more
doaj  

An Empirical Evaluation of Five Small Area Estimators [PDF]

This paper compares five small area estimators. We use Monte Carlo simulation in the context of both artificial and real populations. In addition to the direct and indirect estimators, we consider the optimal composite estimator with population weights ...
Albert Satorra, Alex Costa, Eva Ventura
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Overcoming the High Error Rate of Composite DNA Letters‐Based Digital Storage through Soft‐Decision Decoding

Advanced Science
Composite DNA letters, by merging all four DNA nucleotides in specified ratios, offer a pathway to substantially increase the logical density of DNA digital storage (DDS) systems.
Yaping Xu, Lulu Ding, Shigang Wu, Jue Ruan   +3 more
doaj   +1 more source

Gear Integrated Error Determination Using the Gaussian Template Convolution-Facet Method

Applied Sciences
A gear integrated error, a combination of individual and composite errors, carries richer information and has long been a key target of classic gear error measurement techniques.
Yiming Fang, Zhaoyao Shi, Yanqiang Sun, Pan Zhang   +3 more
doaj   +1 more source

Modeling of Moisture Diffusion in Carbon Braided Composites

International Journal of Aerospace Engineering, 2008
In this study, we develop a methodology based on finite element analysis to predict the weight gain of carbon braided composite materials exposed to moisture. The analysis was based on the analogy between thermal conduction and diffusion processes, which
S. Laurenzi, T. Albrizio, M. Marchetti   +2 more
doaj   +1 more source