Results 191 to 200 of about 288,253 (317)

Risk factors for longitudinal estimated glomerular filtration rate decline in adults with cystic fibrosis. [PDF]

Ann Am Thorac Soc
Nacharaju D, Zelnick LR, Ramos KJ, de Boer IH, Flume PA, Goss CH, Heltshe SL, Bhatraju PK.   +7 more
europepmc   +1 more source

Seismic isolation of foundation by composite liners

, 2020
198
openaire   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Analytical Models and Solutions for Consolidation of Composite Foundation with Long Prefabricated Vertical Drains and Short Stone Columns Based on Virtual Pile Method

工程科学与技术
ObjectiveThe combined composite foundation with long prefabricated vertical drains (PVDs) and short stone columns demonstrates significant engineering benefits in practical applications by integrating reinforcements with varying drainage capacities ...
XU Baolong, LU Mengmeng, ZHANG Xinyan, LIU Yuanjie   +3 more
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Analytical Solution for Composite Foundation with Permeable Pipe Piles Under Uniform Opening Based on Modified Equal Strain Assumption

工程科学与技术
Composite foundation is an effective technology for treating soft ground and is widely used in engineering practices. Permeable pipe piles combine the advantages of the permeability of granular piles with the high bearing capacity of adhesive columns ...
Weitao YANG, Zheng CHEN, Yaru DUAN, Guoxiong MEI   +3 more
doaj  

Thermal Utilization on Chip. [PDF]

Light Sci Appl
Zhang Y, Lai B, Yu F, Li X, Yang Y, Lü W, Jiang K, Sun X, Li D.   +8 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Smart Microneedles Regulate Reactive Oxygen Species and Deliver Matrix Metalloproteinases for Pathological Scar Treatment. [PDF]

ACS Nano
Wu J, Ma J, Li Z, Li J, Hu J, Ma F, Wu Y, Han F, Li B, Xiao C.   +9 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source