Results 261 to 270 of about 2,040,887 (358)

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

open access: yesAdvanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu   +10 more
wiley   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

open access: yesAdvanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen   +14 more
wiley   +1 more source

Composite laminated wakeboard

open access: yesReinforced Plastics, 2008
openaire   +1 more source

Delamination formation, evaluation and suppression during drilling of composite laminates: A review

Composite Structures, 2019
Fiber reinforced composite laminates have been increasingly replacing conventional materials in various manufacturing sectors due to their extremely superior mechanical properties.
Daxi Geng, Yihang Liu, Zhenyu Shao
exaly   +2 more sources

An overview of layerwise theories for composite laminates and structures: Development, numerical implementation and application

Composite Structures, 2019
Over the past decades, a vast number of theories for numerical modeling of laminated composite plates and shells has been developed by various researchers and for diverse reasons.
K M Liew, Zhouzhou Pan, L W Zhang
exaly   +2 more sources

COMPOSITE LAMINATES

2003
High-velocity ice impact   +2 more
semanticscholar   +3 more sources

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