Results 101 to 110 of about 1,550,674 (338)

Quasi-fiber scale modeling of 3D needled composites based on the virtual fiber embedded method

open access: yesMaterials & Design
The objective of this paper is to propose a fiber-level modeling method for simulating tensile fracture of 3D needled composite. The complex fiber structure of 3D needled nonwoven preform is reproduced using virtual fibers.
Jingjing Wang   +6 more
doaj   +1 more source

Flame-retardant composite materials [PDF]

open access: yes
The properties of eight different graphite composite panels fabricated using four different resin matrices and two types of graphite reinforcement are described. The resin matrices included: VPSP/BMI, a blend of vinylpolystyryl pyridine and bismaleimide;
Kourtides, Demetrius A.
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Characterization of injection molded high density polyethylene/rice straw biocomposite [PDF]

open access: yes, 2008
Polymer composite have been subjected to increasing interest, study, and utilization for some decades. The increase in environmental concern rationalize the use of reduce polymeric materials, not only due to their non ...
Adnan, Nurnadia   +3 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Organic Radical-Boosted Ionic Conductivity in Redox Polymer Electrolyte for Advanced Fiber-Shaped Energy Storage Devices

open access: yesNano-Micro Letters
Highlights Developed a versatile HT-based redox polymer electrolyte with exceptional ionic conductivity (73.5 mS cm−1) through self-exchange reaction-based ion hopping mechanism and enhanced polymer chain mobility.
Jeong-Gil Kim   +10 more
doaj   +1 more source

Ablation resistance of C/C-HfC composites

open access: yesCailiao gongcheng
C/C-HfC composites with a density of 2.14 g/cm3 was successfully prepared using an inorganic hafnium solution as a precursor via chemical vapor infiltration (CVI) and precursor infiltration pyrolysis (PIP) methods, and its microstructure and composition ...
ZHENG Peng   +5 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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