Results 41 to 50 of about 1,533,936 (337)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Synthesis of PAN with adjustable molecular weight and low polydispersity index (PDI) value via reverse atom transfer radical polymerization

open access: yesDesigned Monomers and Polymers, 2019
The reverse atom transfer radical polymerization (RATRP) of acrylonitrile (AN) was carried out in N, N-dimethylformamide (DMF) with AIBN as initiator, FeCl3•6H2O/triphenylphosphine (PPh3) and FeCl3•6H2O/pentamethyldle-thylenetrlamlne (PMDETA) as ...
Shuang Li   +8 more
doaj   +1 more source

Effects of heating rate on mechanical and dielectric properties of the Si3N4f/BN/Si3N4 composites by PIP

open access: yesJournal of Materials Research and Technology, 2023
The fabrication of silicon nitride (Si3N4) fiber-reinforced boron nitride (BN) and Si3N4 matrix (Si3N4f/BN/Si3N4) composites with BN interphase through precursor infiltration and pyrolysis (PIP) process is reported. The effects of heating rate during PIP
Nan Meng   +7 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Direct spinning and densification method for high-performance carbon nanotube fibers

open access: yesNature Communications, 2019
The tensile strength of a carbon nanotube fiber is predicted to increase as its constituent nanotubes become more perfectly and densely aligned. Here, the authors present an optimized direct-spinning and chlorosulfonic acid densification method to ...
Jaegeun Lee   +8 more
doaj   +1 more source

LDEF fiber-composite materials characterization [PDF]

open access: yes, 1993
Degradation of a number of fiber/polymer composites located on the leading and trailing surfaces of LDEF where the atomic oxygen (AO) fluences ranged from 10(exp 22) to 10(exp 4) atoms/cm(sup 2), respectively, was observed and compared. While matrices of
Miglionico, C. J.   +3 more
core   +1 more source

Thermal Conductivity of Thermally-Isolating Polymeric and Composite Structural Support Materials Between 0.3 and 4 K

open access: yes, 2008
We present measurements of the low-temperature thermal conductivity of a number of polymeric and composite materials from 0.3 to 4 K. The materials measured are Vespel SP-1, Vespel SP-22, unfilled PEEK, 30% carbon fiber-filled PEEK, 30% glass-filled PEEK,
Barucci   +15 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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