Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
A Crown Ether-Based Covalent Organic Polymer Composite Membrane and Its Application in Molecular Separation. [PDF]
Chen Y +5 more
europepmc +1 more source
Nanoscale β-TCP-Laden GelMA/PCL Composite Membrane for Guided Bone Regeneration. [PDF]
Mahmoud AH +8 more
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Flexible PANI-PVDF Composite Membrane Ammonia Sensor for Chilled Meat Freshness Monitoring. [PDF]
Sun Y, Lin W.
europepmc +1 more source
Composite Membrane Containing Titania Nanofibers for Battery Separators Used in Lithium-Ion Batteries. [PDF]
Lee H, Lee D.
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
PGA-TMC/PTMC/nHA composite membrane with synergistic barrier and osteogenic functions for enhanced bone defect regeneration. [PDF]
Wang J +8 more
europepmc +1 more source
Prediction of CO2 Permeance across ZIF-L@PDMS/PES Composite Membrane. [PDF]
Buddin MMHS, Ahmad AL, Zainuddin MIF.
europepmc +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source

