Results 201 to 210 of about 173,637 (262)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
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Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
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On the Lipid Composition of Membranes
Protoplasma, 1967The lipid content of membrane preparations isolated from different origins has been demonstrated to vary from 30% to 75% on a dry weight basis. Depending on the procedure utilized for the preparation of red cell ghosts, this membrane was found to contain either 30% or 50% lipids, cholesterol and phospholipids, which together account for over 80% of the
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The Composition of Biological Membranes
Archives of Internal Medicine, 1972The main components of biological membranes are proteins, lipids, and carbohydrates in variable proportions. Carbohydrates account for less than 10% of the mass of most membranes and are generally bound either to the lipid or protein components. Myelin has few functions and is made up almost entirely of lipids.
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Membrane distillation by novel hydrogel composite membranes
Journal of Membrane Science, 2016Novel polyelectrolyte hydrogel composites are developed by UV-initiated graft polymerization of acrylic acid and 2-hydroxyethyl methacrylate (functional monomers) and ethylene glycol dimethacrylate (cross-linker), on polypropylene flat sheet membranes (support).
Majidi Salehi S +5 more
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Composition of an amoeba plasma membrane
Biochemical and Biophysical Research Communications, 1971Abstract The plasma membrane of Acanthamoeba castellanii contains per mg of protein 0.6-0.7 μmoles of phospholipid, 0.81-0.98 μmoles of sterol, 1 μmole of non-lipid, organic phosphorus, and 1 μmole of carbohydrate (as glucose). Solutions of the lipid-extracted plasma membrane in 8 M urea separate on Sephadex G-200 into a voided fraction which ...
E D, Korn, T, Olivecrona
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