Results 241 to 250 of about 2,182,425 (310)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Thin-Film Composite Membrane Compaction: Exploring the Interplay among Support Compressive Modulus, Structural Characteristics, and Overall Transport Efficiency. [PDF]

Environ Sci Technol
Xu C, Wang Z, Hu Y, Chen Y.
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Initiating a composite membrane with a localized high iodine concentration layer based on adduct chemistry to enable highly reversible zinc-iodine flow batteries. [PDF]

Chem Sci
Hu Y, Hu T, Zhang Y, Huang H, Pei Y, Yang Y, Wu Y, Hu H, Liang G, Cheng HM.   +9 more
europepmc   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

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On the Lipid Composition of Membranes

Protoplasma, 1967
The lipid content of membrane preparations isolated from different origins has been demonstrated to vary from 30% to 75% on a dry weight basis. Depending on the procedure utilized for the preparation of red cell ghosts, this membrane was found to contain either 30% or 50% lipids, cholesterol and phospholipids, which together account for over 80% of the
openaire   +2 more sources

The Composition of Biological Membranes

Archives of Internal Medicine, 1972
The main components of biological membranes are proteins, lipids, and carbohydrates in variable proportions. Carbohydrates account for less than 10% of the mass of most membranes and are generally bound either to the lipid or protein components. Myelin has few functions and is made up almost entirely of lipids.
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The Composition of Nervous Membranes

1968
Publisher Summary This chapter discusses the four groups of compounds that occur mainly in nervous system and all of them are membrane constituents. These compounds are gangliosides, proteolipids, polyphosphoinositides and neurokeratin. Gangliosides are neuronal components; proteolipids, poly-phosphoinositides and neurokeratin are myelin components ...
openaire   +2 more sources