Results 121 to 130 of about 217,874 (301)

Preparation of a self‐supported zeolite glass composite membrane for CO2/CH4 separation

open access: yesSmart Molecules
The low porosity of metal‐organic framework glass makes it difficult to prepare membranes with high permeability. To solve this problem, we fabricated a series of self‐supported zeolite glass composite membranes with different 4A zeolite loadings using ...
Dudu Li   +5 more
doaj   +1 more source

A Current Overview of Materials and Strategies for Potential Use in Maxillofacial Tissue Regeneration [PDF]

open access: yes, 2017
Tissue regeneration is rapidly evolving to treat anomalies in the entire human body. The production of biodegradable, customizable scaffolds to achieve this clinical aim is dependent on the interdisciplinary collaboration among clinicians, bioengineers ...
Almeida, Luis Eduardo   +7 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Symmetry breaking and other phenomena in the optimization of eigenvalues for composite membranes

open access: yes, 2000
We consider the following eigenvalue optimization problem: Given a bounded domain $\Omega\subset\R^n$ and numbers $\alpha\geq 0$, $A\in [0,|\Omega|]$, find a subset $D\subset\Omega$ of area $A$ for which the first Dirichlet eigenvalue of the operator ...
Chanillo, S.   +4 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Fabrication of Green PVDF/TiO2 Composite Membrane for Water Treatment

open access: yesMembranes
PVDF/TiO2 composite membranes show some potential to be used for water treatment as they combine the advantages of polymers and ceramics. However, conventional PVDF-based composite membranes are always fabricated by using conventional toxic solvents ...
Shuhang Lu, Dong Zou
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A rationally thin composite membrane with differentiated pore structure for industrial-scale alkaline water electrolysis

open access: yesNature Communications
Alkaline water electrolysis is one of the most prospective technologies for large-scale production of green hydrogen. Nevertheless, current porous membranes face the problem of weak ion transport or poor gas barrier performance.
Jian You   +13 more
doaj   +1 more source

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