Results 71 to 80 of about 74,791 (265)
Nonlinear Dynamics of the High-Speed Rotating Plate
International Journal of Aerospace Engineering, 2018 High speed rotating blades are crucial components of modern large aircraft engines. The rotating blades under working condition frequently suffer from the aerodynamic, elastic and inertia loads, which may lead to large amplitude nonlinear oscillations ...
Minghui Yao, Li Ma, Wei Zhang
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Geometry generation principle and meshing properties of a new gear drive
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018 The generation principle of composite cycloid is proposed for the tooth profile of external drive. Firstly, a two-link mechanism is developed as the equivalent mechanism to describe the geometric principle of cycloid by introducing the motion ...
Zhenhua HAN +3 more
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
MachinesThe two-stage proportional valve is a key control component in heavy-duty equipment, where its signal-flow characteristics critically influence operational performance.
Xingyu Zhao +5 more
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Discrete Dynamics in Nature and Society, 2013 This paper investigates the multipulse global bifurcations and chaotic dynamics for the nonlinear oscillations of the laminated composite piezoelectric rectangular plate by using an energy phase method in the resonant case.
Minghui Yao, Wei Zhang
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Design of Computer Numerical Control System for Fiber Placement Machine Based on Siemens 840D sl
SensorsTo address the manufacturing demands of large-scale aerospace composite components, this study systematically investigates the coordinated motion characteristics of multi-axis systems in fiber placement equipment.
Kun Xia +4 more
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