Results 181 to 190 of about 2,099,767 (349)

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Recent advances on entropy analysis of composite nanofluids-A critical review

Results in Engineering
The present study analyzes on the reviews carried out by the previous researchers on the entropy generation caused by the flow and heat transfer of several composite nanofluids subject to varieties of geometries under the influence of several constraints
S.S. Samantaray, A. Misra, S. Shaw, M.K. Nayak, S. Nazari, Imed Boukhris, Ali J. Chamkha   +6 more
doaj  

Counting Composite and Prime Numbers

, 2020
Abstract: The set of positive integers can be divided into different sub-sets, such as the sets of even numbers, of odd numbers, of primes and of composites. Unlike the patterns for even numbers and odd numbers, no repetitive pattern has been identified for readily locating all the primes within the number line and hence by definition to readily locate
openaire   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Characteristics of natural convection heat transfer in composite cavity

Case Studies in Thermal Engineering
In order to study the influence of the nature of the mining airspace on the natural convection heat transfer in the unventilated working face, we establish a numerical model of natural convection in a composite cavity containing porous media by CFD ...
Changkui Lei, Yaoqian Zhu, Suntong Qiu, Chengbo Wang, Ruoyu Bao, Cunbao Deng   +5 more
doaj  

Effect of number of layers and deposition time on layer-by-layer (LbL) composite forward osmosis membrane

, 2020
Annie Lau Ying Ying, Mazrul Nizam Abu Seman   +1 more
openalex   +1 more source

Composite Numbers in an Arithmetic Progression

One challenge (or opportunity!) that many instructors face is how varied the backgrounds, abilities, and interests of students are. In order to simultaneously instill confidence in those with weaker preparations and still challenge those able to go faster, an instructor must be prepared to give problems of different difficulty levels. Using Dirichlet's
Chu, Hung Viet, Miller, Steven J., Siktar, Joshua M.   +2 more
openaire   +2 more sources

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Determining the optimum number of increments in composite sampling

, 2008
John E. Hathaway, G. Bruce Schaalje, R.O. Gilbert, Brent A. Pulsipher, Brett D. Matzke   +4 more
openalex   +2 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source