Results 41 to 50 of about 109,850 (269)

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Stochastic Compositional Optimization with Compositional Constraints

INFORMS Journal on Optimization
Stochastic compositional optimization (SCO) has attracted considerable attention because of its broad applicability to important real-world problems. However, existing work on SCO typically assumes that the projection within a solution update is straightforward, which is not the case for problem instances where constraints are in the form of ...
Shuoguang Yang, Wei You, Zhe Zhang, Ethan X. Fang   +3 more
openaire   +2 more sources

Optimization design, manufacturing and mechanical performance of box girder made by carbon fiber-reinforced epoxy composites

Science and Engineering of Composite Materials, 2018
Optimization design and manufacturing play an important role in obtaining successful composite structures with high efficiency and safe use of materials.
Yang Bin, Tong Lili, Chea Cheav Por
doaj   +1 more source

Multi-objective design optimization of composite submerged cylindrical pressure hull for minimum buoyancy factor and maximum buckling load capacity

Defence Technology, 2021
This paper presents the design optimization of composite submersible cylindrical pressure hull subjected to 3 MPa hydrostatic pressure. The design optimization study is conducted for cross-ply layups [0s/90t/0u], [0s/90t/0u]s, [0s/90t]s and [90s/0t]s ...
Muhammad Imran, Dongyan Shi, Lili Tong, Ahsan Elahi, Hafiz Muhammad Waqas, Muqeem Uddin   +5 more
doaj   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source

Optimized dynamic semantic composition of services [PDF]

Proceedings of the 2008 ACM symposium on Applied computing, 2008
This paper proposes a design for the optimized dynamic (re)composition of services that supports various user requests and accounts for changes in user's context. The composition mechanism relies on semantic descriptions of services' functionality to compose services at runtime.
Sorin M. Iacob, João Paulo A. Almeida, Maria-Eugenia Iacob   +2 more
openaire   +2 more sources

Bridging the Gap in Neuroblastoma Care: Consensus‐Based Statements With Recommendations for Improved Patient and Caregiver Experiences

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma's complex, heterogeneous biology poses significant diagnostic and therapeutic challenges, often requiring caregivers to absorb complex information and participate in time‐sensitive decisions. However, caregivers often feel unprepared to evaluate options.
Vickie Buenger, Joseph Bauer, Jennifer Diamond, Maggie Fader, Shae Hansen, Jacqueline M. Kraveka, Johanna Schoen, Amber Shearer, Dena Sherwood   +8 more
wiley   +1 more source

OPTIMIZATION OF STIFFENED COMPOSITE PLATE USING BALANCING COMPOSITE MOTION OPTIMIZATION

TRA VINH UNIVERSITY JOURNAL OF SCIENCE, 2023
Recently, metaheuristic optimization algorithms have been studied and applied in many fields of engineering, especially in solving structural optimization problems. For structures with complex behaviors, the selection of a suitable optimization algorithm significantly increases the computational efficiency and the accuracy of the solution.
Saren Van Huynh, Vo L Trieu, Phat Thuan Lam, Son Hoai Nguyen   +3 more
openaire   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source