Results 101 to 110 of about 2,461,830 (355)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Study of bonding between glass and plastic in glass-reinforced plastics - extended work Quarterly progress report no. VII, 1 Apr. - 30 Jun. 1966 [PDF]

Bonding between silica glass reinforcement and plastic matrix of glass-reinforced plastic composite ...
Chamberlain, D. L., Jr.
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

EFFECT OF IMPERATA CYLINDRICA REINFORCEMENT FORM ON THE TENSILE AND IMPACT PROPERTIES OF ITS COMPOSITES WITH RECYCLED LOW DENSITY POLYETHYLENE

Acta Polytechnica, 2018
Composites of recycled low-density polyethylene obtained from waste water-sachets and imperata cylindrica were produced with particulate and long-fibre unidirectional mat reinforcements.
Olusola Femi Olusunmade, Abba Emmanuel Bulus, Terwase Kelvin Kashin   +2 more
doaj   +1 more source

A study of low density, high strength high modulus filaments and composites [PDF]

Filament and whisker reinforcement of low density, high strength, high modulus composites - metallic and ceramic layers alternated in multilaminar ...
Alexander, J. A., Shaver, R. G., Withers, J. C.   +2 more
core   +1 more source

Composite intersection reinforcement [PDF]

, 2010
An assembly and method for manufacturing a composite reinforcement for unitizing a structure are provided. According to one embodiment, the assembly includes a base having a plurality of pins extending outwardly therefrom to define a structure about ...
Fuhrer, Jessica J., Funk, Robert S., Misciagna, David T., Tolotta, William S.   +3 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Numerical Integration Study of Penetration and Blasting Damage for Composite Underground Protective Structure with Reinforcement Layers

Buildings
In response to the increasing threat of powerful earth-penetrating weapons, underground protective structures typically employ composite structural systems with reinforced steel layers.
Xingji Zhu, Can Zhao, Longjun Xu, Yujin Wang, Shibin Lin, Guochen Zhao   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Integration of Finite Element Analysis and Machine Learning for Assessing the Spatial-Temporal Conditions of Reinforced Concrete

Buildings
Composite reinforcements are attracting attention in the reinforced concrete (RC) field for their high corrosion resistance, low thermal conductivity, and low electromagnetic interference behavior. However, compared to metallic reinforcements, composites
Junyi Duan, Huaixiao Yan, Chengcheng Tao, Xingyu Wang, Shanyue Guan, Yuxin Zhang   +5 more
doaj   +1 more source