Results 101 to 110 of about 215,542 (310)

Composites with graphene as reinforcement

IOP Conference Series: Materials Science and Engineering, 2019
Abstract In this paper, the developments in the area of graphene-reinforced composite have been reviewed. It also depicts the work guided by the author. In the work, WC powder with 6% cobalt (Co) and graphene (0.2%) in the form of graphene nanoplatelets (GPLs) was prepared by high energy rate ball milling and ultrasonification.
openaire   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A simplified design of a concrete sandwich structure containing a reinforcing rib

Acta Polytechnica CTU Proceedings
This article presents the use of a strut and tie analogy for modelling the behaviour of a concrete sandwich structure, which is formed by thin outer concrete layers made of high-performance concrete and reinforcing ribs. The beams transmitting shear are
Jan Macháček, Eliška Kafková, Věra Kabíčková, Tomáš Vlach   +3 more
doaj   +1 more source

FE modelling of a structurally stitched multilayer composite [PDF]

, 2010
Finite-element models are presented for a typical structurally stitched carbonfibre composite. The term 'structural' means that the stitching yarn is thick enough to form a through-the-thickness reinforcement.
Klimshin, D.V., Koissin, V, Lomov, S.V., Verpoest, I.   +3 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Parametric Investigation of Fatigue-Cracked Tubular T-Joint Repair Using Composite Reinforcement

Engineering Proceedings
Circular hollow sections (CHSs) are widely used in offshore jacket structures due to their excellent compressive strength, torsional resistance, and direction-independent stiffness.
Muhammad Hazim, Saravanan Karuppanan, Mohsin Iqbal   +2 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The influence of pyrolitic degradation on mechanical properties of carbon fibres within recycling composite materials [PDF]

, 2017
The article deals with the influence of thermal pyrolytic degradation on mechanical properties of carbon fibres used in the production of composite material. The carbon fibre has been chosen as the reinforcement of composite and the resin formed a matrix
Glogarová, Veronika, Návrat, Michal, Závada, Jaroslav   +2 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source