Results 41 to 50 of about 1,141,159 (288)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A dielectric sensor for measuring flow in resin transfer moulding. [PDF]

open access: yes, 2000
The development, analysis and experimental validation of a novel flow and cure sensor for use in the resin transfer moulding of composites are presented.
Karkanas, Panagiotis I.   +2 more
core   +1 more source

Evaluation of the color-matching potentials of different universal composite resins with natural tooth structure in class III through-and-through cavities using a visual guide and spectrophotometer [PDF]

open access: yesJournal of Dental Research, Dental Clinics, Dental Prospects
Background. This study assessed the color-matching potentials of Omnichroma single-shade composite resin and Omnichroma Blocker with natural tooth structure in Class III through-and-through restorations and compared them with a universal multi-shade ...
Mahmoud Bahari   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Comparative evaluation of different post and core systems in maxillary molar endodontic treatments: An original study

open access: yesJournal of Pharmacy and Bioallied Sciences
Background: Maxillary molar endodontic treatments require the right post and core system. This study tested cast metal, glass fiber with composite resin, carbon fiber with composite resin, and zirconia post and core materials.
Suneetha Motru   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Erosion of Composite Resins [PDF]

open access: yesJournal of Dental Research, 1980
The surface degradation of composite resins caused by accelerated aging was studied. Accelerated aging for 900 hours caused erosion of the resin matrices and exposure of filler particles. Differences in surface profiles after aging suggest that the materials eroded at different rates. Accelerated aging may model erosive wear of composites.
Powers, John M., Fan, P. L.
openaire   +3 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

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