Results 41 to 50 of about 227,368 (317)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Process for improving mechanical properties of epoxy resins by addition of cobalt ions [PDF]

open access: yes, 1984
A resin product useful as an adhesive, composite or casting resin is described as well as the process used in its preparation to improve its flexural strength mechanical property characteristics.
St.clair, A. K., Stoakley, D. M.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Bibliometric analysis of composite resin restorations from 2000-2020

open access: yesCumhuriyet Dental Journal, 2022
Aim: To indentify the most effective actors(authors, countries, and journals) about composite resin restorations in the period 2000-2020. Material and Methods: An electronis research was conducted in the Scopus database by selecting the words ‘composite ...
Sultan Gizem Ülkü, Nimet Ünlü
doaj   +1 more source

Large boron--epoxy filament-wound pressure vessels [PDF]

open access: yes, 1973
Advanced composite material used to fabricate pressure vessel is prepeg (partially cured) consisting of continuous, parallel boron filaments in epoxy resin matrix arranged to form tape.
Bailey, R. L.   +2 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Comparative evaluation of different post and core systems in maxillary molar endodontic treatments: An original study

open access: yesJournal of Pharmacy and Bioallied Sciences
Background: Maxillary molar endodontic treatments require the right post and core system. This study tested cast metal, glass fiber with composite resin, carbon fiber with composite resin, and zirconia post and core materials.
Suneetha Motru   +5 more
doaj   +1 more source

RF shielded connectors [PDF]

open access: yes, 1974
Gap, where cable joins connector housing, is shielded effectively by composite RF shielding made from suitable potting resin material (fumed silica, thixotropic prepolymer composition), conductive coating (silver-filled, flexible, polyurethane resin ...
Clatterbuck, C., Fisher, A.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Honeycomb-laminate composite structure [PDF]

open access: yes, 1977
A honeycomb-laminate composite structure was comprised of: (1) a cellular core of a polyquinoxaline foam in a honeycomb structure, and (2) a layer of a noncombustible fibrous material impregnated with a polyimide resin laminated on the cellular core.
Gilwee, W. J., Jr., Parker, J. A.
core   +1 more source

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