Results 51 to 60 of about 2,111,207 (385)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Cytotoxicity evaluation of methacrylate- and silorane-based composite resins

open access: yesCumhuriyet Dental Journal, 2012
Objectives: The objective of this study was to investigate and compare the cytotoxic effects of four composite resin materials with different content. Material and Methods: Two traditional methacrylate-based (Clearfil AP-X, RefleXions), as well as a self-
Digdem Eren   +3 more
doaj   +1 more source

In Vitro Evaluation of Gastric Acid and Toothbrushing Effect on the Surface State of Different Types of Composite Resins

open access: yesMedicina, 2022
Background and Objectives: The aim of this in vitro study was to evaluate the effect of gastric acid associated with the effect of toothbrushing on the surface roughness of different types of composite resin used for direct restorations.
Ionuț Tărăboanță   +8 more
doaj   +1 more source

Rheological, processing, and 371 deg C mechanical properties of Celion 6000/N-phenylnadimide modified PMR composites [PDF]

open access: yes, 1985
The rheology, processing, and chemistry of newly developed N-phenylnadimide modified PMR (PMR-PN) polyimide resins are reviewed. The 371 C performance of their composites reinforced with Celion 6000 graphite fibers is also reviewed, along with the state ...
Pater, R. H.
core   +1 more source

Efficiency of polymerization of bulk-fill composite resins: a systematic review.

open access: yesBrazilian Oral Research, 2017
This systematic review assessed the literature to evaluate the efficiency of polymerization of bulk-fill composite resins at 4 mm restoration depth.
A. Reis   +5 more
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Color stability of conventional and bulk fill composite resins

open access: yesRGO: Revista Gaúcha de Odontologia, 2018
Objective: This study compared the color stability of different dental composite resins after prolonged exposure to a coffee solution. Methods: Sixty-four cylindrical discs (10 mm diameter x 2 mm thickness) were prepared using 8 different dental ...
Tamara Carolina TREVISAN   +5 more
doaj   +1 more source

Optimization of graphene-based materials outperforming host epoxy matrices [PDF]

open access: yes, 2015
The degree of graphite exfoliation and edge-carboxylated layers can be controlled and balanced to design lightweight materials characterized by both low electrical percolation thresholds (EPT) and improved mechanical properties.
De Vivo, B.   +9 more
core   +3 more sources

Indirect resin composites

open access: yesJournal of Conservative Dentistry, 2010
Aesthetic dentistry continues to evolve through innovations in bonding agents, restorative materials, and conservative preparation techniques. The use of direct composite restoration in posterior teeth is limited to relatively small cavities due to polymerization stresses.
openaire   +3 more sources

Repair bond strength of nanohybrid composite resins with a universal adhesive

open access: yesActa Biomaterialia Odontologica Scandinavica, 2017
Objective: To investigate the repair bond strength of fresh and aged nanohybrid and hybrid composite resins using a universal adhesive (UA). Materials and methods: Fresh and aged substrates were prepared using two nanohybrid (Venus Pearl, Heraus Kulzer ...
Pinar Altinci   +2 more
semanticscholar   +1 more source

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