Results 51 to 60 of about 2,085,161 (384)
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Adhesive for cryogenic temperature applications [PDF]
Adhesive, which bonds a metal liner to a filament wound composite structure used for cryogenic pressure vessels, prevents the metal liner from buckling under depressurization.
Doyle, H. M.
core +1 more source
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Improving mechanical properties of novel flax/tannin composites through different chemical treatments [PDF]
Due to the inherent environmental benefits of using renewable materials, mimosa tannin resin (a natural phenolic resin) reinforced by flax fibres could offer desirable characteristics (lightweight, economic and low environmental impact) aiming at ...
Abhyankar, Hrushikesh +4 more
core +1 more source
Efficiency of polymerization of bulk-fill composite resins: a systematic review.
This systematic review assessed the literature to evaluate the efficiency of polymerization of bulk-fill composite resins at 4 mm restoration depth.
A. Reis +5 more
semanticscholar +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Cytotoxicity evaluation of methacrylate- and silorane-based composite resins
Objectives: The objective of this study was to investigate and compare the cytotoxic effects of four composite resin materials with different content. Material and Methods: Two traditional methacrylate-based (Clearfil AP-X, RefleXions), as well as a self-
Digdem Eren +3 more
doaj +1 more source
Background and Objectives: The aim of this in vitro study was to evaluate the effect of gastric acid associated with the effect of toothbrushing on the surface roughness of different types of composite resin used for direct restorations.
Ionuț Tărăboanță +8 more
doaj +1 more source
Repair bond strength of nanohybrid composite resins with a universal adhesive
Objective: To investigate the repair bond strength of fresh and aged nanohybrid and hybrid composite resins using a universal adhesive (UA). Materials and methods: Fresh and aged substrates were prepared using two nanohybrid (Venus Pearl, Heraus Kulzer ...
Pinar Altinci +2 more
semanticscholar +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source

