Results 181 to 190 of about 1,552,889 (274)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Experimental and Numerical Analysis of Multiple Low-Velocity Impact Damages in a Glass Fibered Composite Structure. [PDF]

Materials (Basel), 2021
Balasubramaniam K, Ziaja D, Jurek M, Fiborek P, Malinowski P.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Studying the electronic properties of SiO₂/GO/Pb₃O₄/Bi₂O₃ composite structure. [PDF]

Sci Rep
Tiama TM, El-Sayed NM, Abdelaziz NS, Bayoumy AM, Elhaes H, Ibrahim MA.   +5 more
europepmc   +1 more source

Antibiotic cement plate composite structure internal fixation after debridement of bone infection. [PDF]

Sci Rep, 2021
Wang X, Wang S, Xu J, Sun D, Shen J, Xie Z.   +5 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The mechanical characteristics of an aluminum foam winding CFRP composite structure under axial compression. [PDF]

Heliyon
Zhou H, Jiang Y, Yang G, Xie S.
europepmc   +1 more source

Piezoelectric Transducer-Based Diagnostic System for Composite Structure Health Monitoring. [PDF]

Sensors (Basel), 2021
Dragašius E, Eidukynas D, Jūrėnas V, Mažeika D, Galdikas M, Mystkowski A, Mystkowska J.   +6 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Novel Response Surface Technique for Composite Structure Localization Using Variable Acoustic Emission Velocity. [PDF]

Sensors (Basel)
Bhandari B, Maung PT, Prusty GB.
europepmc   +1 more source