This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
In recent years, retrofitting of steel structures has emerged as a major issue in structural engineering and construction management. As the adhesive bond is often the critical aspect controlling the actual performance of steel profiles externally strengthened by composite plates, this paper investigates the bond behavior of fiber reinforced polymer ...
Martinelli, Enzo +3 more
openaire +1 more source
Composite Structure as a Stress Wave Barrier Zone Under Impulse Loading: Microscale Numerical Analysis of Attenuation. [PDF]
Murčinková Z, Sabol D, Baron P.
europepmc +1 more source
Bioinspired Helicoidal Composite Structure Featuring Functionally Graded Variable Ply Pitch. [PDF]
Meo M, Rizzo F, Portus M, Pinto F.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Energy Absorption Characteristics of CFRP-Aluminum Foam Composite Structure Under High-Velocity Impact: Focusing on Varying Aspect Ratios and Relative Densities. [PDF]
Ren J, Liu S, Wang J, Zhao C.
europepmc +1 more source
Research on the Manufacturing Quality of Co-Cured Hat-Stiffened Composite Structure. [PDF]
Ju X, Xiao J, Wang D, Zhao C, Wang X.
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Influence of interface sawtooth angle on the shear behavior of cement mortar coal composite structure. [PDF]
Wang X, Shi X, Bai J, Zhao H, Zhao Y.
europepmc +1 more source
Effect of the Glass Fiber Content of a Polybutylene Terephthalate Reinforced Composite Structure on Physical and Mechanical Characteristics. [PDF]
Hamlaoui O +3 more
europepmc +1 more source

