Results 91 to 100 of about 16,492,262 (312)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Tissue mimicking hydrogel foam materials with mechanical and radiological properties equivalent to human lung

Scientific Reports
The motion of organs and tissues causes X-ray localization error during radiation therapy. Physical phantoms utilizing materials with tissue-equivalent mechanical and radiological properties are therefore desired to simulate organ motion for radiotherapy
Xiangpeng Li, Jihua Gou, Anand P. Santhanam, Chiranjit Maiti, Olusegun J. Ilegbusi   +4 more
doaj   +1 more source

Hybrid composite laminate structures [PDF]

, 1977
An invention which relates to laminate structures and specifically to essentially anisotropic fiber composite laminates is described. Metal foils are selectively disposed within the laminate to produce increased resistance to high velocity impact ...
Chamis, C. C., Lark, R. F.
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Microwave Dynamic Modulation Metasurface Absorber Based on Origami Structure

Optics
With the rapid advancement of detection technologies, traditional static electromagnetic absorbers increasingly struggle to meet controllable stealth requirements across diverse dynamic environments.
Zhaoxu Pan, Qiaobai He, Ruicong Zhang, Tianyu Wang, Jiaqi Zhu, Zicheng Song   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

ACEE composite structures technology [PDF]

Toppics addressed include: advanced composites on Boeing commercial aircraft; composite wing durability; damage tolerance technology development; heavily loaded wing panel design; and pressure containment and damage tolerance in ...
Johnson, Ronald W., Quinlivan, John T., Smith, Peter J., Wilson, Robert D.   +3 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Advances in Shape Memory Polymer Porous Materials: Fabrications, Microstructures, and Applications

Research
As an essential branch of smart materials, shape memory polymer materials (SMPs) have made substantial advances in fabrication strategies, microstructure design, and response methods.
Likai Hu, Fenghua Zhang, Lan Luo, Jinsong Leng   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source