Results 81 to 90 of about 15,021,574 (352)

Composite structural motifs of binding sites for delineating biological functions of proteins [PDF]

, 2011
Most biological processes are described as a series of interactions between proteins and other molecules, and interactions are in turn described in terms of atomic structures.
A Bairoch, A Fiorillo, A Rausell, A Stark, AC Joerger, AC Wallace, AG Murzin, Akira R. Kinjo, AM Schnoes, AR Kinjo, AR Kinjo, AR Kinjo, B Bollobás, B Dasgupta, B Louie, B Rost, BH Dessailly, C Branden, C Winter, CV Robinson, D Petrey, DJ Schuller, DM Chipman, E Krissinel, E Toyota, FP Davis, FP Davis, GM Santos, H Berman, H Kettenberger, Haruki Nakamura, I Friedberg, J Janin, J Shi, J Westbrook, JI Yeh, K Chen, K Henrick, K Kinoshita, K Kinoshita, K Kinoshita, K Okazaki, K Stenberg, L Xie, M Bashton, M Brylinski, M Kitayner, M Levitt, M Moertl, M Nardini, M Tyagi, M Yang, N Nagano, N Tuncbag, N Tuncbag, N Zhao, ND Gold, O Keskin, O Keskin, OC Redfern, Ozlem Keskin, P Cramer, P Shannon, PD Pawelek, R Koike, R Koike, R Rentzsch, R Sinha, RR Thangudu, S Kadono, SF Altschul, T Amemiya, T Kawabata, T Kawabata, TA Holland, TC Terwilliger, Y Loewenstein, Z Aung, ZX Xia   +78 more
core   +5 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Fuselage structure using advanced technology fiber reinforced composites [PDF]

, 1982
A fuselage structure is described in which the skin is comprised of layers of a matrix fiber reinforced composite, with the stringers reinforced with the same composite material.
Robinson, R. K., Tomlinson, H. M.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Foam composite structures [PDF]

The need to include fire resistant foams into state of the art aircraft interior paneling to increase passenger safety in aircraft fires was studied. Present efforts were directed toward mechanical and fire testing of panels with foam inclusions. Skinned
Delano, C. B., Milligan, R. J.
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Influence of Process and Material Parameters on Impact Response in Composite Structure: Methodology Using Design of Experiments [PDF]

, 2010
Even if the mechanical performances of composite materials give new perspectives for the aircraft and space design, the variability of their behavior, linked to the presence of initial microscopic defects or led in service, constitute however a still ...
Garnier, Christian, Mistou, Sébastien, Pantalé, Olivier   +2 more
core   +1 more source

Push-out tests on demountable shear connectors of steel-concrete composite structures

Structures, 2018
The deconstruction of steel-concrete composite structures in buildings and the later separation of the materials is a labour- and cost intensive work.
A. Kozma, C. Odenbreit, Matthias Braun, M. Veljkovic, M. Nijgh   +4 more
semanticscholar   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source