Results 61 to 70 of about 325,156 (310)

A CAI study on transition zones of conventional and Double-Double laminates

Composites Part C: Open Access
Laminate-thickness tapering opportunities of Double-Double (DD) laminates are unique, compared to conventional laminates (denoted as Quad) in aerospace, which are typically composed of 0°, 45°, −45°, 90°plies.
Erik Kappel, Yannick Boose, Mirko Mißbach   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Electronic structures and optical properties of monoclinic ZrO2 studied by first-principles local density approximation + U approach

Journal of Advanced Ceramics, 2017
The electronic structures and optical properties of the monoclinic ZrO2 (m-ZrO2) are investigated by means of first-principles local density approximation (LDA) + U approach.
Jinping Li, Songhe Meng, Jiahong Niu, Hantao Lu   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Cross section shape optimization of wire strands subjected to purely tensile loads using a reduced helical model

Advanced Modeling and Simulation in Engineering Sciences, 2020
This paper introduces a shape optimization of wire strands subjected to tensile loads. The structural analysis relies on a recently developed reduced helical finite element model characterized by an extreme computational efficacy while accounting for ...
Francesco Maria Filotto, Falk Runkel, Gerald Kress   +2 more
doaj   +1 more source

MXene-reduced graphene oxide sponge-based solar evaporators with integrated water-thermal management by anisotropic design

Communications Materials, 2023
The main issue limiting the performance of the solar evaporators is that water-thermal management is difficult to coordinate. Herein, we achieve integrated water-thermal management by designing hierarchical MXene-reduced graphene oxide sponges with ...
Zonglin Liu, Renjie Ding, Fuhua Xue, Xu Zhao, Zhong Chen, Haowen Zheng, Pengyang Li, Qian Yan, Liangliang Xu, Jinhua Xiong, Qingyu Peng, Xiaodong He   +11 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Delamination localisation and length estimation in composite laminate beam by VSHM and pattern recognition methods [PDF]

, 2010
The focus of this work is to investigate the delamination damage in laminate composite beams, to fix a Vibration-based structural health monitoring (VSHM) method for the laminate structures.
Palazzetti, Roberto, Zucchelli, Andrea, Trendafilova, Irina, R. Palazzetti, Minak, Giangiacomo, A. Zucchelli, G. Minak, I. Trendafilova   +7 more
core   +1 more source