Genetic analysis of protein composition of bovine milk
, 2010 This thesis is part of the Dutch Milk Genomics Initiative, and the general aim was to obtain more insight into the genetic background of bovine milk protein composition.
Schopen, G.C.B.
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The effect of probiotic bacteria on community composition, microscale pH and matrix architecture in a saliva-derived model of oral biofilm. [PDF]
J Oral MicrobiolReichardt E +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Comparison of air displacement plethysmography and octopolar multifrequency bioelectrical impedance analysis in NCAA Division I male lacrosse athletes. [PDF]
PeerJSawyer JC, Hurrell JE.
europepmc +1 more source
Exploring Composition Studies Sites, Issues, Perspectives
Intro -- Contents -- Foreword: Defining Composition Studies . . . Again, and Again - Andrea A. Lunsford -- Introduction: How Did We Get Here? - Kelly Ritter and Paul Kei Matsuda -- I: The State of the Field(s) -- 1.
Matsuda, Associate Professor Paul Kei. +3 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The long-term impact of racial and ethnic school composition on late-life cognition, depressive symptoms, and overall health among older US Latinos. [PDF]
Am J EpidemiolGutierrez S +3 more
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The Relationship Between Meal Composition and the Body Composition of Wroclaw Medical University Students. [PDF]
NutrientsJaremków A +6 more
europepmc +1 more source