Results 61 to 70 of about 1,217,119 (341)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

The Collision of Two Lexicons: Librarians, Composition Instructors and the Vocabulary of Source Evaluation

Evidence Based Library and Information Practice, 2016
Objective – The study has two aims. The first is to identify words and phrases from information literacy and rhetoric and composition that students used to justify the comparability of two sources. The second is to interpret the effectiveness of students’
Toni M. Carter, Todd Aldridge
doaj   +1 more source

Pluggable AOP: Designing Aspect Mechanisms for Third-party Composition

, 2005
Studies of Aspect-Oriented Programming (AOP) usually focus on a language in which a specific aspect extension is integrated with a base language. Languages specified in this manner have a fixed, non-extensible AOP functionality. In this paper we consider
Kojarski, Sergei, Lorenz, David H.
core   +3 more sources

The Composition Of Normative Groups And Diagnostic Decision Making: Shooting Ourselves In The Foot [PDF]

, 2006
Purpose: The normative group of a norm-referenced test is intended to provide a basis for interpreting test scores. However, the composition of the normative group may facilitate or impede different types of diagnostic interpretations.
Pena, Elizabeth D., Plante, Elena, Spaulding, Tammie J.   +2 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Response: An Invitation to a Too-Long Postponed Conversation: Race and Composition by Octavio Pimentel [PDF]

, 2013
Octavio Pimentel’s “Racism and Composition: Redesigning the Composition Classroom to be more Culturally Inclusive” critically provokes pedagogical and programmatic questions by focusing on pressing issues of race and language within a historical context ...
Medina, Cruz
core   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

PECULIARITIES OF THE MUSICAL LANGUAGE AND COMPOSITION IN SNEJANA PÎSLARI’S COMPOSITION FOR PIANO TREI PORTRETE MUZICALE: СHOPIN, SKRIABIN, RACHMANINOV [PDF]

Studiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2022
The author of the given article analyzes the piano composition by Snejana Pâslari „Trei portrete musicale” examined in terms of its content and form. The conclusion is made that the musical language and the specifics of composition and dramaturgy of this
CABACOV, DMITRI
doaj  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Variable elimination for building interpreters [PDF]

, 2010
In this paper, we build an interpreter by reusing host language functions instead of recoding mechanisms of function application that are already available in the host language (the language which is used to build the interpreter).
Cohen, Julien, Giavitto, Jean-Louis, Michel, Olivier   +2 more
core   +3 more sources