Results 81 to 90 of about 5,911,827 (272)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Second Language Writing: Research Insights for the Classroom. Second Language Writing: Research Insights for the Classroom.

open access: yesIlha do Desterro, 2008
The study of composition at the post-secondary level is a relatively new practice which has become widespread only during the past half-century. More recent is the emergence over the past two to three decades of composition studies as an academic ...
Madeleine Youmans
doaj  

Syntactic Interference of the Indonesian Language in Intermediate-Level German Composition

open access: yesJournal of Languages and Language Teaching
This study examines the phenomenon of syntactic interference arising from the structural differences between Indonesian (L1) and German (L2) in compositions written by B1-level students.
Rount Maulero, Hayatul Cholsy
doaj   +1 more source

Insights into Low-Resource Language Modelling: Improving Model Performances for South African Languages [PDF]

open access: yesJournal of Universal Computer Science
To address the gap in natural language processing for Southern African languages, our paper presents an in-depth analysis of language model development under resource-constrained conditions.
Ruan Visser   +2 more
doaj   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

The Collision of Two Lexicons: Librarians, Composition Instructors and the Vocabulary of

open access: yesEvidence Based Library and Information Practice, 2016
Objective – The study has two aims. The first is to identify words and phrases from information literacy and rhetoric and composition that students used to justify the comparability of two sources. The second is to interpret the effectiveness of students’
Toni M. Carter, Toni M. Carter
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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