Results 61 to 70 of about 5,911,827 (272)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Visões da língua(gem) em comentários sobre internetês não é língua portuguesa

Filologia e Linguística Portuguesa, 2006
This paper aims to discuss the representation that university students of letters and pedagogy courses use in the so-called “internetês”, a grapholinguistic form which has been spread in digital genres such as chats, blogs and social networks as the ...
Fabiana Komesu
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Interpreting language-learning data [PDF]

, 2020
This book provides a forum for methodological discussions emanating from researchers engaged in studying how individuals acquire an additional language.
Gudmestad, Aarnes; Virginia Polytechnic Institute and State University, Huang, Xiaoliang; Beijing Foreign Studies University, Leclercq, Pascale; Université Paul Valéry Montpellier 3, Trévisiol, Pascale; Université Paris 3 & DILTEC EA 2288, Watorek, Marzena; Université Paris 8 & UMR-SFL, CNRS, Scheuer, Sylwia; University of Paris 3 – Sorbonne Nouvelle, Horgues, Céline; University of Paris 3 – Sorbonne Nouvelle, Majdoub, Hedi; Université Paris 8 & UMR-SFL, CNRS, Yu, Xinyue Cécilia; Inalco - CNRS - EHESS, CRLAO, Pélissier, Maud; University of Agder, Rast, Rebekah; American University of Paris & UMR-SFL, CNRS, Søfteland, Åshild; Østfold University College, Guan, Qianwen; City University of Hong Kong, Emilsen, Linda Evenstad; Østfold University College, Hilton, Heather E.; Université Lumière Lyon 2, Edmonds, Amanda, Leclercq, Pascale, Osborne, John; Université Savoie Mont Blanc, Gudmestad, Aarnes   +18 more
core   +1 more source

Can creative writing in Latin support students' confidence in and enjoyment of A Level prose composition?

The Journal of Classics Teaching
This research aims to explore the ways in which creative writing may be used as a pedagogical tool in the Latin language classroom, in particular how creative writing may benefit students in Latin prose composition.
Emily Romain
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Third language acquisition: Age, proficiency and multilingualism [PDF]

, 2020
This book deals with the phenomenon of third language (L3) acquisition. As a research field, L3 acquisition is established as a branch of multilingualism that is concerned with how multilinguals learn additional languages and the role that their ...
Gudmundson, Anna, Sleeman, Petra, Sánchez, Laura, Sciutti, Sandro, Bardel, Camilla, Salaberry, Rafael, Muñoz, Carmen, Stadt, Rosalinde, Pfenninger, Simone E., Hulk, Aafke   +9 more
core   +1 more source

Lookback supports semi-parallel, just-in-time processing in second language written composition.

PLoS ONE
PurposeCompetent written production results from semi-parallel processes that flow from content determination to finger movement. Information from upstream processes that is not used immediately is easily lost.
Evgeny Chukharev, Jens Roeser, Mark Torrance   +2 more
doaj   +2 more sources

The communicative role of composition in the design of an advertising poster

Архитектон
The article presents the results of a theoretical study of the problem of communication in the design of an advertising poster. The communicative function of composition in design is examined, and the influence of means and techniques of composition on ...
Kucherova Alina V.
doaj   +1 more source