Results 161 to 170 of about 2,817 (257)

Selection for Function in Early Life: Implications for Early-Onset Pathologies. [PDF]

Evol Appl
Asselin K, Dujon AM, Capp JP, Lemaître JF, Pirard F, Vaiman D, Ujvari B, Pujol P, DeGregori J, Nedelcu AM, Thomas F.   +10 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Microbiome differential abundance methodologies to detect relevant taxa associated with chemotherapy toxicity rate in colorectal cancer. [PDF]

Bioinform Adv
Martín-De Arribas E, Conde-Pérez K, Aja-Macaya P, Vallejo JA, Bou G, López-Cheda A, Jácome-Pumar MA, Ladra S, Poza M.   +8 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Microbiome mediation analysis: methods, assumptions, and practical considerations. [PDF]

Front Cell Infect Microbiol
Jiang Z, Li G.
europepmc   +1 more source

Is Compositionality an A Priori Principle?

, 2005
openaire   +3 more sources

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Reconciling flexibility and efficiency: medial entorhinal cortex represents a compositional cognitive map. [PDF]

Nat Commun
Piray P, Daw ND.
europepmc   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

A neural circuit framework for economic choice: From building blocks of valuation to compositionality in multitasking. [PDF]

Neuron
Battista A, Padoa-Schioppa C, Wang XJ.
europepmc   +1 more source