Results 131 to 140 of about 31,809 (283)

Copper‐Catalyzed Defluorinative Allylboration of Allenes with Trifluoromethyl Alkenes

open access: yesChemistryEurope, Volume 4, Issue 1, January 2026.
A copper‐catalyzed borylative coupling of allenes with 1‐trifluoromethyl alkenes is reported. The reaction selectively provides synthetically versatile borylated 1,1‐difluoro‐1,5‐dienes that can be converted into a range of medicinally relevant fluorinated compounds. Mechanistic studies reveal a key role of the catalytically generated LiCl by assisting
Martín Piñeiro‐Suárez   +3 more
wiley   +1 more source

Biosafety Evaluation of 6,7‐Dihydroxy‐3‐(2‐Nitrophenyl)Coumarin in Human Cells

open access: yesJournal of Applied Toxicology, Volume 46, Issue 1, Page 198-206, January 2026.
ABSTRACT Coumarins are considered a privileged scaffold in medicinal chemistry, as they may interact with biological macromolecules, presenting several pharmacological properties. Their potential makes them an object of study for the evaluation of their safety for humans, which is essential in the design of a potential drug.
Júlia Zocca Nunes de Barros   +3 more
wiley   +1 more source

Gaps Between European Crohn's Colitis Organisation Quality Standards of Care and the Real World in Special Situations in Inflammatory Bowel Disease Across Europe: Results From E‐QUALITY Survey

open access: yesJCC Plus, Volume 1, Issue 1, January 2026.
ABSTRACT Background Managing special situations in Inflammatory Bowel Disease (IBD)—such as surgery, nutrition, acute severe ulcerative colitis (ASUC) and paediatric‐to‐adult transition—is critical for patient outcomes. The European Crohn's and Colitis Organisation's (ECCO) E‐QUALITY initiative aimed to identify gaps between its evidence‐based care ...
Gionata Fiorino   +24 more
wiley   +1 more source

Over‐Tourism: A Review and Research Agenda

open access: yesGlobal Business and Organizational Excellence, Volume 45, Issue 2, Page 227-245, January/February 2026.
ABSTRACT Managing tourism destinations is essential for ensuring the sustainable tourism development of both the tourism industry and the communities that host tourists and visitors. An issue which has risen in prominence in the post‐pandemic era is over‐tourism posing significant threats to the environment, economy, and social well‐being of ...
Komathi Wasudawan, Marc Arul Weissmann
wiley   +1 more source

Protocol for the injection of adenoviruses into brown adipose tissue in mice. [PDF]

open access: yesSTAR Protoc
Prida E   +8 more
europepmc   +1 more source

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