Results 61 to 70 of about 122,093 (281)

How thick is a fault? Fault displacement-thickness scaling revisited [PDF]

open access: yes, 2006
No abstract ...
Bright, A.M.   +4 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Dynamic Modeling and Analysis of Rolling Bearing with Compound Fault on Raceway and Rolling Element

open access: yesShock and Vibration, 2020
Rolling element bearing is a very important part of mechanical equipment and widely used in rotating machinery. Rolling element bearings could appear localized defects during the working condition, which would cause the complex vibration response of ...
Xin Zhang   +5 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Empirical evaluation of accuracy of mathematical software used for availability assessment of fault-tolerant computer systems [PDF]

open access: yes, 2012
Dependability assessment is typically based on complex probabilistic models. Markov and semi-Markov models are widely used to model dependability of complex hardware/software architectures.
Kharchenko, V. S.   +3 more
core  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Intelligent Diagnosis of Compound Faults of Gearboxes Based on Periodical Group Sparse Model

open access: yesApplied Sciences
A gearbox compound fault intelligent diagnosis method based on the period group sparse model is proposed for the problem that the fault features are coupled with each other and the fault components are superimposed on each other and difficult to be ...
Lan Chen   +4 more
doaj   +1 more source

Solid state bistable power switch [PDF]

open access: yes, 1970
Tin and copper provide high current and switching time capabilities for high-current resettable fuses. They show the best performance for trip current and degree of reliability, and have low coefficients of thermal ...
Bartko, J., Shulman, H.
core   +1 more source

The "MIND" Scalable PIM Architecture [PDF]

open access: yes, 2005
MIND (Memory, Intelligence, and Network Device) is an advanced parallel computer architecture for high performance computing and scalable embedded processing.
Brodowicz, Maciej, Sterling, Thomas
core   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

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