Results 111 to 120 of about 871,936 (333)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Discipliner la compréhension par l’exercice du résumé

Repères, 2018
We observe how thirty teachers use summarising exercises in sequences of reading lessons at different levels. Our research aims to describe different uses of summarising activities based on two variables: i) the variable of the text involved and ii) the ...
Christophe Ronveaux, Bernard Schneuwly
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

THE CORRELATION BETWEEN FISCALITY RATE, GDP AND TAX INCOMES. CASE STUDY ROMANIA AND TURKEY [PDF]

The academic literature analyzes the fiscality concern from all points of view, and the question which pressed upon the theoreticians and also the practitioners of the last decades remains: which is the adequate level of the fiscality?
Cristea, Mirela, Dracea, Raluca, Ionascu, Costel, Irtes, Meltem   +3 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Compréhension de textes et lésion cérébrale droite : une étude de cas multiples

Glossa, 2019
La compréhension d’un texte est une activité complexe faisant intervenir différents processus linguistiques et cognitifs susceptibles d’être altérés après une lésion cérébrale droite. Toutefois, on constate un manque de consensus relatif à l’atteinte
Aurore Dubos, Géraldine Marc-Venet, Sophie Ferrieux, Marie Nogues-Lasiaille, Sophie Chesneau   +4 more
doaj  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Métaphores et dessins comme voies d’accès aux représentations des apprenants sur la compréhension orale [PDF]

Synergies Mexique, 2016
Dans cet article nous présentons une partie des résultats d’une recherche faite auprès d’étudiants et de professeurs de français et d’anglais du Centre d’enseignement de langues étrangères (CELE) de l’Université Nationale Autonome du Mexique (UNAM) sur ...
Silvia López del Hierro, María Teresa Mallén Estebaranz   +1 more
doaj  

Sémantique inférentielle et compréhension des verbatim clients

SHS Web of Conferences, 2012
Partant des deux postulats suivants : 1. la structuration sémantique des textes peut être décrite au moyen de l’inférence. 2. il existe au moins trois niveaux d’inférence : lexicale, discursive et pragmatique, nous étudions trois types d'inférences ...
Massoussi Taoufik, Doucy Geoffrey
doaj   +1 more source