Results 111 to 120 of about 38,039 (305)
This paper considers the transfer of approaches from the field of to the field of to be used in decision support systems. The most relevant of the developed approaches will be roughly introduced and it will be considered how these approaches can be ...
Apeldoorn, Daan
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Comprehensibility Improvement of Tabular Knowledge Bases
This paper discusses the important issue of knowledge base comprehensibility and describes a technique for comprehensibility improvement. Comprehensibility is often measured by simplicity of concept description.
Maximilian Riesenhuber +3 more
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Toward a dynamic view of second language comprehensibility [PDF]
This study took a dynamic approach to second language (L2) comprehensibility, examining how listeners construct comprehensibility profiles for L2 Spanish speakers during the listening task and what features enhance or diminish comprehensibility ...
Bergeron, Annie +5 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A narrative review on do’s and don’ts in prescription label writing – lessons for pharmacists
Nithushi R Samaranayake,1 Wasana GRSK Bandara,2 Chinthana MGA Manchanayake2 1Department of Allied Health Sciences, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka; 2Colombo South Teaching Hospital, Kalubowila, Dehiwala,
Samaranayake NR +2 more
doaj
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Comprehensibility in Language Assessment
Comprehensibility is considered central to successful communication (Munro & Derwing, 1995a, 2007). Yet, despite the crucial role it plays in communication and the contribution it makes towards the assessment of spoken language ability, comprehensibility
Cooke, Sheryl, Tavakoli, Parvaneh
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Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Towards a new model of readability [PDF]
This thesis attempts to develop a new model for a renewed concept of readability. The thesis begins by discussing the rationale for carrying out this research. Next, the extensive literature around the topic of readability is reviewed.
Dahlia Janan,
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