Results 111 to 120 of about 1,193,065 (342)

Experimental Approaches to Referential Domains and the On-Line Processing of Referring Expressions in Unscripted Conversation

open access: yesInformation, 2011
This article describes research investigating the on-line processing of language in unscripted conversational settings. In particular, we focus on the process of formulating and interpreting definite referring expressions.
Sarah Brown-Schmidt   +1 more
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

An Evaluation of Age Effects on Driver Comprehension of Flashing Traffic Signal Indications using Multivariate Multiple Response Analysis of Variance Models [PDF]

open access: yes, 2001
Objective: The objective of this experiment was to identify whether drivers comprehended traffic signals differently when turning left at signalized intersections where traffic signals were in “flashing mode” operation.
Drakopoulos, Alexander   +1 more
core   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

From First Steps to Full Acquisition: Comprehension of Subjunctive Clauses in Bilectal Children With Down Syndrome and Typical Language Development

open access: yesFrontiers in Communication, 2018
Previous work on linguistic abilities of individuals with Down syndrome (DS) suggests severe impairment of complex syntactic structures in a number of languages. Given difficulties reported with comprehension and production of relative clauses and object
Christiana Christodoulou   +4 more
doaj   +1 more source

Some comprehension problems in kindergarten, [PDF]

open access: yes, 1956
Thesis (M.A.)--Boston ...
Baron, Rose Perlmuter   +3 more
core   +1 more source

Comprehensibility and comprehensiveness of financial analysts’ reports

open access: yesStudies in Communication Sciences, 2015
Abstract Financial analysts and their texts play a key role in the financial community. Despite their importance, both the analysts as writers and the texts themselves are widely under-researched, as a review of the literature in the field reveals. This is the gap that our large research project on financial analysts’ written communication aims to ...
Marlies Whitehouse-Furrer, Daniel Perrin
openaire   +2 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

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