Results 261 to 270 of about 585,619 (290)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

When to switch captions off? Exploring the effects of L2 proficiency and vocabulary knowledge on comprehension of captioned and uncaptioned TV

Geòrgia Pujadas, Carmen Muñoz
openalex   +2 more sources

Assessing the rereading effect of digital reading through eye movements using artificial neural networks. [PDF]

Front Psychol
Xu Y, Liang M, Jin Y, Wang L, Gao W, Tao T.   +5 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The importance of intonation for children's understanding of verbal irony. [PDF]

Front Psychol
Smith J, Glenwright M.
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Does preoperative anxiety influence endodontic skill performance and students' subjective perceptions in an observational simulation-based study? [PDF]

BMC Med Educ
Var E, Cam Y, Pektas E, Kuden C.
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Examining the impact of augmented reality on students' learning outcomes. [PDF]

Sci Rep
Tian X, Ironsi CS.
europepmc   +1 more source

Mediational effects of reading-related intermediate phenotypes from polygenic scores to reading skills. [PDF]

NPJ Sci Learn
Remon A, Mascheretti S, Voronin I, Feng B, Ouellet-Morin I, Brendgen M, Vitaro F, Robaey P, Andlauer TFM, Boivin M, Dionne G.   +10 more
europepmc   +1 more source