Results 81 to 90 of about 585,619 (290)

Protein kinase FAM20C—when subcellular localization matters

FEBS Letters, EarlyView.
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley   +1 more source

Supporting English Language Learners through ICT [PDF]

CSIE Working Papers Series, 2017
Teaching students to be literate is a high educational priority in the Republic of Moldova, as it is certainly throughout the world. The purpose of the article is to show why the classroom environment undergoes a constant change, and how teachers face ...
Serghei VASILACHI
doaj  

Perceptions and understanding of organ donation among medical undergraduates in Southeastern Nigeria [PDF]

Scripta Medica
Background/Aim: Organ donation continues to be acknowledged globally as the preferred treatment for individuals with end-stage organ diseases. So far, it is one of the greatest advances of modern science and has resulted in many patients getting a new ...
Njelita Ifeoma Anne, Akabuike Josephat Chukwudi, Eyisi Ifeanyi Gabriel, Nwachukwu Chinyerem Cynthia, Ezenyeaku Chijioke Amara, Nonye Juliana Ezeonyejiaku, Mbomson Onyinye Paschaline   +6 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

A comparison of effectiveness of two hemisphere training on reading and comprehension of visual and auditory types of dyslexic students

مجله علوم روانشناختی, 2019
Background: The effectiveness of neuropsychological therapeutic methods on neurodevelopmental disorders, including dyslexia, has been reviewed in many researches.
Roya nabizadeh Nodehi, Ahmad Borjali, Mahnaz Esteki, Noorali Farrokhi   +3 more
doaj  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Experimental Approaches to Referential Domains and the On-Line Processing of Referring Expressions in Unscripted Conversation

Information, 2011
This article describes research investigating the on-line processing of language in unscripted conversational settings. In particular, we focus on the process of formulating and interpreting definite referring expressions.
Sarah Brown-Schmidt, Agnieszka E. Konopka   +1 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source