Results 181 to 190 of about 13,939,585 (375)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

‘Dyslexia-friendly’ approaches in the teaching practice of Croatian English as a foreign language (EFL) teachers listening comprehension tests

, 2017
Agnieszka Kałdonek‐Crnjaković, Zrinka Fišer   +1 more
openalex   +2 more sources

New Automatic Hybrid Approach for Tracking Learner Comprehension Progress in the LMS

, 2022
Khalid Benabbes, Brahim Hmedna, Khalid Housni, Ahmed Zellou, Ali El Mezouary   +4 more
openalex   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

The Effects of Collaborative and Non- Collaborative Approaches to Teaching Reading Strategies on Iranian efl Learners’ Reading Comprehension and Attitude toward Reading

, 2020
Azadeh Rajaei, Seyed Hassan Talebi, Shirin Abadikhah   +2 more
openalex   +2 more sources

Teaching Reading Comprehension Through Genre-Based Approach (GBA) at Senior High School

, 2022
Gunawan Gunawan
openalex   +2 more sources

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Looking for a more comprehensive approach

, 2013
The necessity/convenience for improving accuracy in determining the flood frequency is widely accepted further than among hydrologists, and is increasingly deepened in relationship with the statement of different thresholds related to the respective management systems.
Diez Gonzalez, Jose Javier, Paz Doel, Rosa Maria, Monnot, Julien Victor   +2 more
openaire   +2 more sources

Methodological remarks for the achievement of readingcomprehension in the university context

Educación y Sociedad
The development of the reading comprehension skill is one of the most important purposes inthe Cuban National Education System. Reading favors the acquisition of linguistic habitsand skills, and improves the linguistic communication process as a way of ...
Yudiel Oliva-Rodriguez, Rogelio Pérez-Parrado, Adolfo Miguel Alfaro-Llanes   +2 more
doaj   +1 more source