Results 111 to 120 of about 3,769,215 (284)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

A Systematic Review of Green Port Evaluation: Methods, Subjects, and Indicators

open access: yesJournal of Marine Science and Engineering
In the context of global carbon neutrality goals and the transition to clean energy, ports have become a focal point due to their significant energy consumption and pollution emissions. This heightened attention has promoted research on green ports, with
Huaping Fei, Hongda Shi, Xinying Pan
doaj   +1 more source

Straight-line programs with memory and matrix Bruhat decomposition

open access: yes, 2013
We advocate that straight-line programs designed for algebraic computations should be accompanied by a comprehensive complexity analysis that takes into account both the number of fundamental algebraic operations needed, as well as memory requirements ...
Niemeyer, Alice C.   +2 more
core  

Two-Loop Vertices in Quantum Field Theory: Infrared and Collinear Divergent Configurations

open access: yes, 2006
A comprehensive study is performed of two-loop Feynman diagrams with three external legs which, due to the exchange of massless gauge-bosons, give raise to infrared and collinear divergencies.
Actis   +66 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

A Comprehensive Framework for Controlled Query Evaluation, Consistent Query Answering and KB Updates in Description Logics [PDF]

open access: yes, 2018
In this extended abstract we discuss the relationship between confidentiality-preserving frameworks and inconsistency-tolerant repair and update semantics in Description Logics (DL).
Lembo, Domenico   +2 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Software fault characteristics: A synthesis of the literature [PDF]

open access: yes, 2015
Faults continue to be a significant problem in software. Understanding the nature of these faults is important for practitioners and researchers. There are many published fault characteristics schemes but no one scheme dominates.
Bowes, D   +4 more
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

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