Results 21 to 30 of about 64,648 (216)

Nationwide Real‐World Modeling of Surgical Outcomes in Elderly Patients: Incorporating Geriatric‐Specific Risk Factors Into Prediction of Mortality and Morbidity

Annals of Gastroenterological Surgery
Aim As the aging population grows, it is crucial to evaluate the quality of surgical care considering geriatric‐specific factors and outcomes. The aim of this study was to develop and validate prediction models for mortality and morbidity in patients ...
Naoya Sato, Hiraku Kumamaru, Mitsukazu Gotoh, Yoshihiro Kakeji, Yuko Kitagawa, Yasuyuki Seto, Hiromi Rakugi, Masahiro Akishita, Kazue Nakajima, Arata Takahashi, Hiroaki Miyata, Shigeru Marubashi   +11 more
doaj   +1 more source

Muscle Ultrasound as Imaging Domain of Frailty

Frontiers in Medicine, 2022
IntroductionFrailty is a geriatric syndrome, a clinical state of vulnerability for developing dependency and/or death. Due to its multidimensional nature, Comprehensive Geriatric Assessment (CGA) constitutes the best strategy to evaluate frailty in older
Leonardo Bencivenga, Leonardo Bencivenga, Francesco Picaro, Lorenzo Ferrante, Klara Komici, Federico Ruggiero, Immacolata Sepe, Giuseppina Gambino, Grazia Daniela Femminella, Grazia Daniela Femminella, Dino Franco Vitale, Nicola Ferrara, Nicola Ferrara, Carlo Rengo, Giuseppe Rengo, Giuseppe Rengo   +15 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Geriatric Rehabilitation in Patients with Frailty: Interim Results of the POSTSCRIPTUM. An Open Prospective Study [PDF]

Вестник восстановительной медицины
INTRODUCTION. Introduction of additional stage of rehabilitation in elderly patients with varying degrees of frailty into practice helps to restore functional independence in patients, reduce the frequency of rehospitalizations and mortality in this ...
Olga N. Tkacheva, Nadezhda K. Runikhina, Irina P. Malaya, Albert R Yusupov, Natalia V. Sharashkina, Valentina S. Ostapenko, Yulia V. Kotovskaya, Elen A. Mkhitaryan, Maria S. Arefieva, Evgenii Е. Popov, Elnura E. Esenbekova   +10 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Functional Status Geriatric Scores: Single-Handed Tools for 30-Day Mortality Risk After Hip Fracture

Clinical Interventions in Aging, 2021
Carmen da Casa,1 Carmen Pablos-Hernández,1,2 Alfonso González-Ramírez,1,2 Juan F Blanco1,3 1Instituto de investigación biomédica de Salamanca (IBSAL), Salamanca, Spain; 2Othogeriatric Unit, Hospital Universitario de ...
da Casa C, Pablos-Hernández C, González-Ramírez A, Blanco JF   +3 more
doaj  

Comprehensive geriatric assessment — the main tool for the work of a geriatrician

Российский журнал гериатрической медицины, 2023
A comprehensive geriatric assessment is the main diagnostic tool in the work of a geriatrician, which is also necessary for drawing up an individual plan for managing an older patient.
N. V. Sharashkina, O. N. Tkacheva, N. K. Runikhina, M. S. Arefieva, K. A. Eruslanova, V. S. Ostapenko, Yu. V. Kotovskaya   +6 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source