Results 81 to 90 of about 59,555 (253)

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

open access: yesAdvanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang   +19 more
wiley   +1 more source

Syncope is associated with multidimensional frailty in older adults

open access: yesBMC Geriatrics
Background Multidimensional frailty and syncope are common in older adults, yet their relationship remains unclear. Methods This retrospective multicenter study, involving outpatients who underwent Comprehensive Geriatric Assessment, aims to evaluate the
Francesco Curcio   +13 more
doaj   +1 more source

Synthetic MRI Neuroimaging Correlates of Frailty: Correlations Between Frailty Scales and Brain Structural Integrity

open access: yesAGING MEDICINE, EarlyView.
Frailty was associated with decreased gray and white matter brain volumes in older adults. Synthetic MRI further revealed relaxometry alterations correlated with frailty severity across multiple clinical scales. ABSTRACT Objectives Frailty, a common condition in the elderly, is characterized by a decline in physiological reserves and an increased ...
Yuhui Chen   +7 more
wiley   +1 more source

Geriatric Helper: An mHealth Application to Support Comprehensive Geriatric Assessment

open access: yesSensors, 2018
The Comprehensive Geriatric Assessment (CGA) is a multidisciplinary diagnosis approach that considers several dimensions of fragility in older adults to develop an individualized plan to improve their overall health.
Samuel Silva   +2 more
doaj   +1 more source

Biomarkers of Sarcopenia: Current Status and Future Perspectives

open access: yesAGING MEDICINE, EarlyView.
In this review, we summarize the various biomarkers discovered in recent years, including biochemical, imaging, and physical testing markers. We analyze their advantages and disadvantages and propose potential ways to improve the diagnostic accuracy of biomarkers, as well as future research directions.
Bijin Luo   +6 more
wiley   +1 more source

A survey among hospital members of the Italian Hospital and Territory Society

open access: yesGeriatric Care
To describe hospital activities distributed across the national territory, we conducted an online survey, addressed to all hospital members of the Italian Hospital and Territory Society (SIGOT) by email, and disseminated using SIGOT social channels. The
Filippo Fimognari   +6 more
doaj   +1 more source

GERIATRIC HEALTH ASSESSMENT AND HEARING LOSS

open access: yesНаука и инновации в медицине, 2018
Aim - to examine the results of a comprehensive geriatric assessment depending on the degree of hearing loss. Material and methods. We examined 110 patients aged from 60 to 90 years with bilateral symmetrical impairment of the hearing function.
T Yu Vladimirova, L V Aizenshtadt
doaj   +1 more source

Defining Frailty in Chinese‐Language Biomedical Literature (2014–2024): A Decade of Conceptual Evolution

open access: yesAGING MEDICINE, EarlyView.
Frailty definitions in Chinese‐language biomedical literature increasingly align with international frameworks, while retaining conceptual diversity, underscoring the need for multidimensional, cross‐cultural research and integration with traditional Chinese medicine for culturally sensitive clinical practice.
Haodong Wei   +5 more
wiley   +1 more source

Costs of medication in older patients: before and after comprehensive geriatric assessment

open access: yesClinical Interventions in Aging, 2018
Gulcin Done Unutmaz,1 Pinar Soysal,2 Busra Tuven,1 Ahmet Turan Isik3 1Department of Internal Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey; 2Geriatric Center Kayseri Education and Research Hospital, Kayseri, Turkey; 3Department of
Unutmaz GD, Soysal P, Tuven B, Isik AT
doaj  

Chances and challenges of comprehensive geriatric assessment training for healthcare providers

open access: yesGeriatric Care, 2018
Geriatrics is the medical specialty that deals with physical, psychological, social and functional aspects of the older adult and represents a most authentic form of personalized medicine.
Maria Cristina Polidori   +1 more
doaj   +1 more source

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