Results 81 to 90 of about 64,648 (216)

Comprehensive geriatric assessment and palliative care

Aging Medicine
The geriatric vision of palliative care is based on a multidisciplinary, patient‐centered approach, looking for a balance between human dignity and medical treatments with a particular focus on the social and ethical aspects. In order to develop the best
Alberto Castagna, Vincenzo Militano, Carmen Ruberto, Ciro Manzo, Giovanni Ruotolo   +4 more
doaj   +1 more source

Incidence and Disease Course of Polymyalgia Rheumatica During Two Decades: A Nationwide Study Across Health Care Sectors in Denmark

Arthritis &Rheumatology, EarlyView.
Objective A new algorithm enables the identification of patients with polymyalgia rheumatica (PMR) across health care sectors in Denmark. We estimated annual incidence rates from 2003 to 2024 and described the disease course, including the occurrence of late‐onset giant cell arteritis (GCA) and prednisolone or prednisone (PDN) treatment.
Agnete Overgaard Donskov, Ellen Margrethe Hauge, Annette De Thurah, Mette Nørgaard, Kresten Krarup Keller   +4 more
wiley   +1 more source

Exploring the potential of cluster analysis in identifying disease phenotypes in CPPD: Moving from intuition to insight

Arthritis &Rheumatology, Accepted Article.
Background Calcium pyrophosphate deposition (CPPD) disease is a heterogeneous condition and is frequently misdiagnosed due to the different clinical presentations and variable disease progression. Aim of this study is to identify clinical phenotypes of CPPD disease by integrating real‐world data from two datasets. Methods Data from the COLCHICORT trial
Greta Pellegrino, Laurène Norberciak, Silvia Sirotti, Abhishek Abhishek, Mariano Andrès, Edoardo Cipolletta, Julien Damart, Renaud Desbarbieux, Pilar Diez, Vincent Ducoulombier, Hang‐Korng Ea, Emilio Filippucci, Charlotte Jauffret, Augustin Latourte, Jean‐Guillaume Letarouilly, Sébastien Ottaviani, Laura Pezzoni, Pascal Richette, Pierre Robinet, Georgios Filippou, Tristan Pascart   +20 more
wiley   +1 more source

Arthroscopic Allogeneic Bone Strip Grafting for Recurrent Shoulder Dislocation With Critical Glenoid Bone Loss: A Free Graft Suspension Fixation Technique

Arthroscopy Techniques, EarlyView.
Abstract In patients with recurrent anterior shoulder dislocation and glenoid bone loss between 10% and 20%, isolated Bankart repair remains associated with a certain rate of postoperative redislocation. The optimal management for this patient subset is controversial. We describe an all‐arthroscopic technique using allogeneic bone strips for free graft
Yingbin Wu, Jiang Guo, Weitong Liu, Changbing Wang, Chuying Fu, Lilian Zhao   +5 more
wiley   +1 more source

L‐Shaped Three‐Portal Configuration for Arthroscopic Double‐Row Suture Repair of Lafosse Type III and IV Subscapularis Tears

Arthroscopy Techniques, EarlyView.
Abstract Lafosse type III and IV subscapularis tendon injuries are severe rotator cuff tears. Current repair uses anterolateral, anterior, and lateral portals, which have restricted visualization and difficult maneuverability. This technical note describes an L‐shaped three‐portal (LST) combination: anterosuperolateral, anteroinferolateral, and ...
Gang Li, Feifei Shen, Wei Sun, Shaobo Li, Dedong Cui, Hui Luan, Xingtao Ge   +6 more
wiley   +1 more source

Arthroscopic Latissimus Dorsi Transfer in the Lateral Decubitus Position for Irreparable Posterosuperior Massive Rotator Cuff Tears

Arthroscopy Techniques, EarlyView.
Abstract The management of irreparable posterosuperior massive rotator cuff tears remains challenging. With advances in arthroscopic techniques, minimally invasive arthroscopic latissimus dorsi tendon (LDT) transfer has been increasingly used for irreparable posterosuperior massive rotator cuff tears.
Yang Yang, JianMin Zhang, Peng Wang, QingGuo Zhang, YongZhi Ye, XiaoBo Zhou   +5 more
wiley   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Evaluation of a pantoprazole and 4‐desmethylpantoprazole‐sulfate metabolic ratio as a novel CYP2C19 phenotyping method

British Journal of Clinical Pharmacology, EarlyView.
Aims CYP2C19 is one of the most important pharmacogenes, and its activity is highly variable due to factors such as genetics or drug–drug interactions. Due to the lack of an appropriate endogenous CYP2C19 biomarker, surrogate methods to assess its activity are warranted.
Julian Peter Müller, Vladimir N. Belov, Sabrina Yamoune, Bob Miller, Mohammed Hasoumi, Jolanta Tupiec, Thea Laurentius, L. Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

Sarcopenia Severity and the Accumulation of Geriatric Syndromes Among Older Adults: A Cross-Sectional Study from Vietnam

Geriatrics
Background/Objectives: Sarcopenia frequently coexists with other geriatric syndromes, and its severity may influence their clinical manifestation. This study examines the prevalence of geriatric syndromes in older adults with non-severe and severe ...
Huong Thi Thu Nguyen, Vasi Naganathan, Thanh Xuan Nguyen, Tam Ngoc Nguyen, Thu Thi Hoai Nguyen, Huyen Thi Thanh Vu, Anh Lan Nguyen, Vien Chi Le, Narelle Warren, Hoa Lan Nguyen, Robert J. Goldberg, Anh Trung Nguyen   +11 more
doaj   +1 more source

Quercetin‐zinc coordination polymer coated CaCO3 nanoparticles potentiate radiotherapy through reprogramming tumor immunosuppression

BMEMat, EarlyView.
Synthesis of QZCaCO3‐PEG to synergistically enhance the immunogenicity of radiotherapy through concurrent Zn2+‐induced cancer cell pyroptosis and Que‐mediated hypoxia amelioration through sequentially suppressing TGF‐β secretion and ECM deposition. Abstract Radiotherapy has demonstrated broad applications in treating solid tumors, but the hostile tumor
Chunjie Wang, Hengze Ding, Yu Hao, Honglin An, Ziliang Dong, Minming Chen, Yujie Zhu, Quguang Li, Bin Huang, Liangzhu Feng   +9 more
wiley   +1 more source