Results 191 to 200 of about 231,910 (293)

Precision medicine in paediatrics: Progress and priorities

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain   +3 more
wiley   +1 more source

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis   +4 more
wiley   +1 more source

Formative feedback to improve pharmacology learning: Proposed principles and guidelines for effective practice

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims To learn effectively, students need timely, specific, actionable feedback—known as formative feedback—on what and how well they are learning and on how to improve further. Providing effective feedback to help students learn pharmacology is a complex task.
Thomas Anthony Angelo
wiley   +1 more source

Gastroparesis: A Comprehensive Overview of Pathophysiology, Etiology, Diagnosis, and Multidisciplinary Management

open access: yes
Gastroparesis is a chronic, often debilitating disorder of gastric motility defined by objectively delayed gastric emptying in the absence of mechanical obstruction, with symptoms persisting for at least three months. The clinical presentation—dominated by nausea, vomiting, early satiety, postprandial fullness, bloating, and abdominal pain&mdash ...
openaire   +1 more source

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb–Drug Interaction Investigation

open access: yesBiopharmaceutics &Drug Disposition, EarlyView.
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula   +4 more
wiley   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

open access: yesBMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu   +5 more
wiley   +1 more source

Understanding Barriers to Cancer Pain Management: Insights From Patients and Healthcare Professionals-A Systematic Review. [PDF]

open access: yesPublic Health Chall
Admassie BM   +11 more
europepmc   +1 more source

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