Comprehensive Two-Dimensional Gas Chromatography as a Bioanalytical Platform for Drug Discovery and Analysis [PDF]
Pharmaceutics, 2023 Over the last decades, comprehensive two-dimensional gas chromatography (GC×GC) has emerged as a significant separation tool for high-resolution analysis of disease-associated metabolites and pharmaceutically relevant molecules.
Atiqah Zaid +3 more
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30th Anniversary of comprehensive two‐dimensional gas chromatography: Latest advances [PDF]
Analytical Science Advances, 2021 In this review, we report on the latest (2020‐Early 2021) instrumental advances and applications of comprehensive two‐dimensional gas chromatography (GC×GC), including its hyphenation with novel upstream or downstream processes (sample preparation ...
Delphine Zanella +2 more
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Candida Species (Volatile) Metabotyping through Advanced Comprehensive Two‐Dimensional Gas Chromatography [PDF]
Microorganisms, 2020 Microbial metabolomics is a challenge strategy that allows a comprehensive analysis of metabolites within a microorganism and may support a new approach in microbial research, including the microbial diagnosis.
Carina Pedrosa Costa +3 more
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Comprehensive Two-Dimensional Gas Chromatography–Mass Spectrometry Analysis of Exhaled Breath Compounds after Whole Grain Diets [PDF]
Molecules, 2021 Exhaled breath is a potential noninvasive matrix to give new information about metabolic effects of diets. In this pilot study, non-targeted analysis of exhaled breath volatile organic compounds (VOCs) was made by comprehensive two-dimensional gas ...
Kaisa Raninen +5 more
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Classification of Botrytized Wines Based on Producing Technology Using Flow-Modulated Comprehensive Two-Dimensional Gas Chromatography [PDF]
Foods, 2021 The enantiomeric ratio of chiral compounds is known as a useful tool to estimate wine quality as well as observe an influence of wine-producing technology.
Olga Vyviurska +4 more
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Rapid Determination of Methamphetamine, Methylenedioxymethamphetamine, Methadone, Ketamine, Cocaine, and New Psychoactive Substances in Urine Samples Using Comprehensive Two-Dimensional Gas Chromatography [PDF]
MetabolitesBackground/Objectives: This study evaluates the applicability of a comprehensive two-dimensional gas chromatography−flame ionisation detection (GC×GC−FID) approach for the simultaneous determination of 12 underivatised psychoactive drugs, including new ...
Doreen N. B. Chandra Siri +4 more
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Characterization of Aroma Compounds in Cooked Sorghum Using Comprehensive Two-Dimensional Gas Chromatography-Time-of-Flight Mass Spectrometry and Gas Chromatography-Olfactometry-Mass Spectrometry [PDF]
Molecules, 2021 Sorghum is the major raw material for the production of Chinese Baijiu (Chinese liquor) and has a great effect on the flavor of Baijiu. Volatiles in cooked glutinous and non-glutinous sorghum samples were extracted using solid-phase microextraction (SPME)
Shuang Chen +5 more
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Comprehensive two‐dimensional gas chromatography‐mass spectrometry: A review [PDF]
Mass Spectrometry Reviews, 2008 AbstractAlthough comprehensive two‐dimensional gas chromatography (GC × GC) has been on the scene for more than 15 years, it is still generally considered a relatively novel technique and is yet far from being fully established. The revolutionary aspect of GC × GC, with respect to classical multidimensional chromatography, is that the entire sample is ...
Peter Tranchida +2 more
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Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics. [PDF]
Trends Analyt Chem, 2018 Due to excellent separation capacity for complex mixtures of chemicals, comprehensive two-dimensional gas chromatography (GC × GC) is being utilized with increasing frequency for metabolomics analyses. This review describes recent advances in GC × GC method development for metabolomics, organismal sampling techniques compatible with GC × GC ...
Keppler EAH +3 more
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Sorbent‐Based Sampling With Two‐Stage Trapping/Desorption Coupled to Comprehensive Two‐Dimensional Gas Chromatography and Mass Spectrometry for Terpenoids Profiling in Cannabis [PDF]
Analytical Science AdvancesCannabis inflorescences represent an important source of many high‐value bioactive specialized metabolites, among which the family of terpenes or terpenoids that are the largest classes of natural products known.
Marco De Poli +5 more
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