Results 101 to 110 of about 1,168,560 (301)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Light transport and general aviation aircraft icing research requirements [PDF]

open access: yes
A short term and a long term icing research and technology program plan was drafted for NASA LeRC based on 33 separate research items. The specific items listed resulted from a comprehensive literature search, organized and assisted by a computer ...
Breeze, R. K., Clark, G. M.
core   +1 more source

A needs and resource assessment approach to developing a comprehensive dental plan for Boston's Head Start program [PDF]

open access: yes, 1979
Thesis (M.Sc.)--Boston University, Henry M. Goldman School of Graduate Dentistry, 1979 (Dental Public Health).Includes bibliographical references: (leaves 49-50)
Project Head Start (US)   +1 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Chrysanthemum indicum Flavonoid Extract on the Oxidative Stress Resistance of Caenorhabditis elegans

open access: yesShipin gongye ke-ji
To investigate the in vivo antioxidant activity of flavonoid extract from Chrysanthemum indicum and its effects on oxidative stress resistance, this study evaluated the effects of Chrysanthemum indicum flavonoid extract on the antioxidant enzyme ...
Hailin CUI   +5 more
doaj   +1 more source

Trusted Hands: The Role of Community-Based Organizations in Enrolling Children in Public Health Insurance Programs [PDF]

open access: yes, 2010
Trusted Hand is a new approach to enrolling traditionally hard-to-reach children in public health insurance programs. While the most common locations for enrollment assistance are state and local social service agencies and health clinics, many states ...
Debbi S. Main   +2 more
core  

Research of Comprehensive Utilization of Coal Gangue

open access: yesDEStech Transactions on Engineering and Technology Research, 2018
Oil and coal are abundant in China and it is a superiority for the development. Coal gangue come from the course of coal exploitation, and processing, which is one of the solid wastes of industry biggest in emission of our country. How to solve this environment pollution and effectively utilize the coal gangue is a main subject and difficult problem ...
JIA HAN   +3 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The utility of comprehensive coagulation assays

open access: yesJapanese Journal of Thrombosis and Hemostasis, 2022
Shoko FURUKAWA, Keiji NOGAMI
openaire   +1 more source

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