Results 131 to 140 of about 1,168,560 (301)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The golden genome annotation of Ganoderma lingzhi reveals a more complex scenario of eukaryotic gene structure and transcription activity

open access: yesBMC Biology
Background It is generally accepted that nuclear genes in eukaryotes are located independently on chromosomes and expressed in a monocistronic manner. However, accumulating evidence suggests a more complex landscape of gene structure and transcription ...
Lining Wang   +9 more
doaj   +1 more source

Global and Episodic Bundling: An Overview and Considerations for Medicaid [PDF]

open access: yes, 2011
Examines implementation issues for two payment strategies under which a group of providers receives a single payment per patient for a predefined time period for a predefined set of services and which involve risk adjustment and quality ...
Gwyn Volk, James Pettersson
core  

A Comprehensive Evaluation of Emergency Department Utilization by Patients With Cirrhosis

open access: yesAmerican Journal of Gastroenterology
INTRODUCTION: Emergency department (ED)-based care is required for cirrhosis management, yet the burden of cirrhosis-related ED healthcare utilization is understudied. We aimed to describe ED utilization within a statewide health system and compare the outcomes of high ED use (HEDU) vs non-HEDU in individuals with cirrhosis.
Swetha Parvataneni   +11 more
openaire   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Analysis and Research on Associated Elements Nb, Zr, Ga and Sc in Sedimentary Rare Earth Ores

open access: yesKuangchan zonghe liyong
Through comparative studies of different digestion methods for five ore samples with varying grades collected from adjacent mining areas in Yunnan and Guizhou Provinces, combined with optimization of instrumental parameters and accuracy precision tests ...
Shujun LIU   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Determination of Sulfate Ion in Ferric Oxide Powder by Ion Chromatography

open access: yesKuangchan zonghe liyong
To establish a method for the determination of sulfate ion in ferric oxide powder by ion chromatography with suppression conductivity detector. The hydrochloric acid was used to decomposed samples, with 1.0 mmol/L sodium bicarbonate and 3.2 mmol/L sodium
Yong LEI   +5 more
doaj   +1 more source

Advancing Community Health Worker Practice and Utilization: The Focus on Financing [PDF]

open access: yes, 2006
There is a growing interest in the use of community health workers in various roles in the US health care system. These workers go by various titles and names -- including promotora and community health advisor -- but all assist members of the ...
Catherine Dower   +3 more
core  

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