Results 51 to 60 of about 480,998 (248)

Compressive Holography

open access: yesOptics Express, 2009
Compressive sampling enables signal reconstruction using less than one measurement per reconstructed signal value. Compressive measurement is particularly useful in generating multidimensional images from lower dimensional data. We demonstrate single frame 3D tomography from 2D holographic data.
David J, Brady   +4 more
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The role of twinning and stacking fault-induced plasticity on the mechanical properties of aluminum-lithium-graphene nanocomposites

open access: yesNanocomposites
In this study, the synthesis-structure-property relationship of graphene-reinforced Al matrix nanocomposites was investigated. The Al-Li-GNPs nanocomposite was synthesized to attain both high strength and good ductility.
Sara I. Ahmad   +2 more
doaj   +1 more source

Analysis of the prospects of the application of the electroplastic effect in the processes of processing metals with pressure

open access: yesЛитьë и металлургия, 2020
The mechanical properties of metals change temporarily or permanently under the influence of a high density electric current in the deformation zone. This phenomenon is called electroplasticity, and its use makes it possible to intensify the process of ...
D. V. Minko
doaj   +1 more source

Mechanical Behavior of Briquettes Made from a Mixture of Sawdust and Rice Husks for Commercialization

open access: yesResources, 2022
The development of this research work seeks to determine the mechanical behavior of the compacted mixture of pine sawdust and rice husk by varying the mass percentages of these biomasses obtained in briquettes, with the purpose of being marketed.
Oscar Araque   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

COMPRESSIVE SENSING

open access: yesInternational Journal of Engineering Technologies and Management Research, 2020
Compressive sensing is a relatively new technique in the signal processing field which allows acquiring signals while taking few samples. It works on two principles: sparsity, which pertains to the signals of interest, and incoherence, which pertains to the sensing modality.
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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