Results 61 to 70 of about 868,109 (319)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Geochronology of the felsic rocks in Orijärvi, southern Finland – implications for stratigraphy [PDF]

open access: yesEstonian Journal of Earth Sciences
The Orijärvi area within the Paleoproterozoic Uusimaa belt contains volcanic and minor sedimentary formations, providing valuable insights into the oldest Svecofennian crust in southern Finland.
Elisa Toivanen   +4 more
doaj   +1 more source

Arrhythmia Diagnosis by Using Level-Crossing ECG Sampling and Sub-Bands Features Extraction for Mobile Healthcare

open access: yesSensors, 2020
Mobile healthcare is an emerging technique for clinical applications. It is usually based on cloud-connected biomedical implants. In this context, a novel solution is presented for the detection of arrhythmia by using electrocardiogram (ECG) signals. The
Saeed Mian Qaisar, Syed Fawad Hussain
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A New Way to Store Simple Text Files

open access: yesAlgorithms, 2020
In the era of ubiquitous digitization, the Internet of Things (IoT), information plays a vital role. All types of data are collected, and some of this data are stored as text files.
Marcin Lawnik   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Acoustic properties and low strain rate behavior of different types of chocolate

open access: yesInternational Journal of Food Properties, 2023
Five different chocolate types (i.e. extra dark, dark, milk, white, and ruby) were characterized and compared for the acoustical and textural characteristics.
Šárka Nedomová   +7 more
doaj   +1 more source

Colour volumetric compression for realistic view synthesis applications

open access: yes, 2011
Colour volumetric data, which is constructed from a set of multi-view images, is capable of providing realistic immersive experience. However it is not widely applicable due to its manifold increase in bandwidth.
Bull, David   +4 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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