Results 61 to 70 of about 1,931,160 (313)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Bardoxolone Methyl Ameliorates Compression-Induced Oxidative Stress Damage of Nucleus Pulposus Cells and Intervertebral Disc Degeneration Ex Vivo

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Intervertebral disc degeneration (IDD) is the main cause of low back pain, and little is known about its molecular and pathological mechanisms. According to reports, excessive compression is a high-risk factor for IDD; compressive stress can induce ...
Yueyang Tian   +5 more
doaj   +1 more source

Clustering by compression

open access: yes, 2004
We present a new method for clustering based on compression. The method doesn't use subject-specific features or background knowledge, and works as follows: First, we determine a universal similarity distance, the normalized compression distance or NCD ...
Cilibrasi, Rudi, Vitanyi, Paul
core   +4 more sources

Compressive Holography

open access: yesOptics Express, 2009
Compressive sampling enables signal reconstruction using less than one measurement per reconstructed signal value. Compressive measurement is particularly useful in generating multidimensional images from lower dimensional data. We demonstrate single frame 3D tomography from 2D holographic data.
David J, Brady   +4 more
openaire   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The role of twinning and stacking fault-induced plasticity on the mechanical properties of aluminum-lithium-graphene nanocomposites

open access: yesNanocomposites
In this study, the synthesis-structure-property relationship of graphene-reinforced Al matrix nanocomposites was investigated. The Al-Li-GNPs nanocomposite was synthesized to attain both high strength and good ductility.
Sara I. Ahmad   +2 more
doaj   +1 more source

Analysis of the prospects of the application of the electroplastic effect in the processes of processing metals with pressure

open access: yesЛитьë и металлургия, 2020
The mechanical properties of metals change temporarily or permanently under the influence of a high density electric current in the deformation zone. This phenomenon is called electroplasticity, and its use makes it possible to intensify the process of ...
D. V. Minko
doaj   +1 more source

THE NECESSITY OF COMPRESSION GARMENTS IN MANAGING LYMPHEDEMA

open access: yesJournal of Cancer Rehabilitation, 2022
Background Lymphedema affects millions of cancer patients and survivors in the United States (US). The consequences of inadequately treated lymphedema include physiological changes that signi cantly impact their quality of life.
Said Nafai   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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