Results 61 to 70 of about 250,620 (292)

DISCRETE ATOMIC COMPRESSION OF DIGITAL IMAGES

open access: yesРадіоелектронні і комп'ютерні системи, 2018
The subject matter of this paper is the discrete atomic compression (DAC) of digital images, which is a lossy compression process based on the discrete atomic transform (DAT). The goal is to investigate the efficiency of the DAC algorithm.
Iryna Victorivna Brysina   +1 more
doaj   +1 more source

Compressive sensing using the modified entropy functional [PDF]

open access: yesDigital Signal Processing, 2014
In most compressive sensing problems, @?"1 norm is used during the signal reconstruction process. In this article, a modified version of the entropy functional is proposed to approximate the @?"1 norm. The proposed modified version of the entropy functional is continuous, differentiable and convex.
Kivanc Kose, Osman Gunay, A. Enis Cetin
openaire   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Robust Steganography by Modifying Sign of DCT Coefficients

open access: yesIEEE Access, 2019
Modern adaptive image steganography with minimizing a distortion function has high performance of undetectability. However, when an image with hidden information is attacked by JPEG compression, its robustness cannot be guaranteed, that remarkably limits
Zhiqiang Zhu   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Lossless Compression Algorithm Based on Hybrid Coding of Adaptive Huffman and Golomb-Rice for WSN [PDF]

open access: yesJisuanji gongcheng, 2016
Aiming at the problem that traditional Wireless Sensor Network(WSN) data compression algorithms cannot take both compression efficiency and data loss into account,a fast and efficient Lossless Adaptive Compression(LAC) algorithm based on adaptive Huffman
XIE Ruiyun,HAI Benzhai
doaj   +1 more source

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