Results 51 to 60 of about 484,851 (292)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Sustainable prediction of compression index in fine-grained soils using machine learning techniques

Open Geosciences
The accurate prediction of ultimate settlement is of critical importance for the longevity of structures, as it helps prevent structural damage and functional deterioration.
İmamoğlu Tuncay, Sert Sedat, Bol Ertan, Özocak Aşkın, Arslan Eylem, Bağca İrem, Kocaman Kadir, Özsağır Mustafa, Akmaz Emre   +8 more
doaj   +1 more source

Compression of ultrashort UV pulses in a self-defocusing gas

, 2009
Compression of UV femtosecond laser pulses focused into a gas cell filled with xenon is reported numerically. With a large negative Kerr index and normal dispersion, xenon promotes temporal modulational instability (MI) which can be monitored to shorten ~
Berge, L., Koehler, C., Skupin, S.
core   +1 more source

Designing microstructured polymer optical fibers for cascaded quadratic soliton compression of femtosecond pulses [PDF]

, 2008
The dispersion of index-guiding microstructured polymer optical fibers is calculated for second-harmonic generation. The quadratic nonlinearity is assumed to come from poling of the polymer, which in this study is chosen to be the cyclic olefin copolymer
Ashihara, Bache, Bache, Bache, Bache, Bache, Baum, Birks, Birks, Blow, Brabec, Chang, DeSalvo, Faccio, Guo, Ilday, Johnson, Kazansky, Khanarian, Krolikowski, Kuhlmey, Liu, Lægsgaard, Lægsgaard, Menyuk, Mollenauer, Morten Bache, Moses, Moses, Moses, Stegeman   +30 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A Study on Developing a Model for Predicting the Compression Index of the South Coast Clay of Korea Using Statistical Analysis and Machine Learning Techniques

Applied Sciences
As large cities are continually being developed around coastal areas, structural damage due to the consolidation settlement of soft ground is becoming more of a problem.
Sungyeol Lee, Jaemo Kang, Jinyoung Kim, Wonjin Baek, Hyeonjun Yoon   +4 more
doaj   +1 more source

The Dynamic Lymphaticovenular Anastomosis for Breast Cancer–related Lymphedema without Compression: Salvaging Lymphedema Patients Who Lost Conservative Treatment Opportunity

Plastic and Reconstructive Surgery, Global Open, 2023
Background:. In conservative treatment for breast cancer–related lymphedema (BCRL), compression therapy has a crucial role. However, some BCRL patients are unable to use compression, and then their lymphedema continues to worsen as they miss treatment ...
Yukio Seki, MD, PhD, Akiyoshi Kajikawa, MD, PhD, Rintaro Asai, MD, Mayo Tomochika, MD, PhD, Hitoshi Nemoto, MD, PhD, Takahiro Terashima, MD, PhD, Norimitsu Kurogi, MD   +6 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Effect of Degree of Saturation on Consolidation Parameters of Fine-Grained Soils

Bulletin of the Mineral Research and Exploration
Terzaghi (1943)'s theory of consolidation phenomenon has some limitations for unsaturated geological environments in nature. Additionally, soils are subjected to consolidation tests under partially saturation conditions.
Kamil Kayabalı, Deniz Yılmaz
doaj   +1 more source